Hypofractionated Image-Guided Radiation Therapy of the Spine: Analysis of Factors Associated with Local Tumor Control


Hypofractionated radiation therapy plays an important role in the treatment of primary and metastatic spinal tumors. This treatment modality is used as stand-alone therapy or as an operative adjuvant. The results of single-fraction radiation have allowed us to alter our surgical technique and goals. Hypofractionated radiation has not been studied to the same extent as single-fraction radiation. A retrospective chart and imaging review will be conducted in order to determine local tumor control provided by this therapy, and multivariate statistical modeling will be used in order to delineate factors that may be predictive of treatment success. This information will help determine which patients may benefit the most from hypofractionated radiation therapy and which patients should undergo a different treatment.

Project Type

Clinical Research

Preferred Project Dates

  • June 15 – August 7
  • June 22 – August 14
Student's Role

The student will play a key role in gathering patient information and will work closely with their faculty sponsors in reviewing relevant imaging studies. Furthermore, the student will participate in statistical analysis of the data. Upon completion of the analysis, the student will co-author a manuscript describing the findings for publication in a scientific journal.

Extent of Research/Laboratory, Clinical, and Didactic Activities
  • Clinical Research: 75%
  • Clinical Activities (Time attending clinics, shadowing, and/or OR observation): 15%
  • Didactics (Lab, DMT meetings, and/or other weekly conferences): 10%

Summer Fellowship Online Application