Find By Last Name: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

A

• Allis, C. David
  Molecular Biology
  The histone code and its impact on gene regulation and chromosome dynamics.
  
• Allison, James P.
  Immunology
  The T cell antigen receptor complex and its effect on T cell proliferation, survival, and cytokine production.
  
• Altan-Bonnet, Grégoire
  Computational Biology
  Robustness and adaptability in T cell ligand discrimination.
  
• Anderson, Kathryn V.
  Developmental Biology
  Genetic pathways that direct embryonic patterning and morphogenesis in the mouse embryo.
  

B

• Bao, Zhirong
  Developmental Biology
  How the genome dictates development, with C. elegans as our models.
  
• Baylies, Mary K.
  Developmental Biology
  The mechanisms underlying the specification and morphogenesis of organ systems using Drosophila muscle development as a model system.
  
• Benezra, Robert
  Cancer Biology and Genetics
  Molecular mechanisms of tumor growth and progression using mouse Id1 and Id3 knock-out models and analysis of the spindle assembly checkpoint.
  
• Besmer, Peter
  Developmental Biology
  Normal and oncogenic receptor tyrosine kinase signaling in virto and in vivo in mice.
  
• Blasberg, Ronald G.
  Molecular Pharmacology and Chemistry
  Development of non-invasive imaging paradigms in living organisms using radionuclide and optical reporter systems.
  
• Bromberg, Jacqueline
  Medicine
  Aberrantly activated Stat3 and the mechanisms of Stat3-mediated transformation.
  

C

• Cartegni, Luca
  Molecular Pharmacology and Chemistry
  Role of alternative splicing events in the development and/or maintenance of cancer.
  
• Chaganti, Raju S.K.
  Cell Biology
  Genomic instability in cancer cells and its implications for clinical behavior of tumors and normal cellular developmental pathways.
  
• Chapman, Paul B.
  Immunology
  Medicine
  Mechanisms by which the immune system recognizes cancer and the development of effective immunotherapy treatments.
  
• Chaudhuri, Jayanta
  Immunology
  Mechanistic elucidation of immunoglobulin gene diversification.
  
• Cheung, Nai-Kong V.
  Pediatrics
  Development of curative therapies for the treatment of metastatic childhood solid tumors with special emphasis on antibody-based strategies.
  
• Chiosis, Gabriela
  Molecular Pharmacology and Chemistry
  Pharmacological modulation of molecular chaperones in transformed systems.
  

D

• Danishefsky, Samuel J.
  Molecular Pharmacology and Chemistry
  Synthesis of antitumor natural products and of fully synthetic carbohydrate-based vaccines.
  
• Denzin, Lisa K.
  Immunology
  Regulation of class II MHC antigen processing by HLA-DM and HLA-DO.
  
• Dupont, Bo
  Immunology
  Receptor-ligand interactions regulating NK cell activation/inhibition; signal transduction pathways in NK cells; and NK cells in tumor immunosurveillance and hematopoietic stem cell transplantation.
  

E

F

• Fagin, James
  Human Oncology and Pathogenesis Program
  Pathogenesis of thyroid cancer, role of oncogenic kinases.
  
• Fisher, Robert P.
  Molecular Biology
  Control of the cell cycle by the network of cyclin-dependent kinases and CDK-activating kinases.
  
• Fong, Yuman
  Surgery
  Herpes-based oncolytic viral therapies in the treatment of malignancy.
  
• Fuks, Zvi
  Molecular Pharmacology and Chemistry
  Mechanisms of radiation-induced damage and the clinical basis of radiation resistance.
  
• Funabiki, Hironori
  Cell Biology
  Regulation of the structure and configuration of chromosomes during the cell division cycle.
  

G

• Gerald, William L.
  Human Oncology and Pathogenesis
  Identification and characterization of molecular alterations in human cancers that are responsible for clinically relevant features of the disease.
  
• Giancotti, Filippo
  Cell Biology
  Signaling by adhesion receptors during tumor progression and angiogenesis.
  
• Gin, David Y.
  Molecular Pharmacology and Chemistry
  Synthesis of complex glycoconjugate immunostimulants and anti-cancer, anti-viral natural products.
  
• Glickman, Michael
  Immunology
  Molecular mechanisms underlying the pathogenesis of Mycobacterium tuberculosis and mechanisms of nonhomologous end-joining in mycobacteria.
  
• Goldberg, Jonathan
  Structural Biology
  Structural and biochemical characterization of intracellular vesicle transport.
  

H

• Hadjantonakis, Anna-Katerina
  Developmental Biology
  Use mouse genetics and high-resolution imaging of living samples to study the developmental pathways that direct and orchestrate the establishment of the mammalian body plan.
  
• Hall, Alan
  Cell Biology
  Rho and Ras GTPases and the control of cell migration, morphogenesis, and polarity.
  
• Hammerling, Ulrich G.
  Immunology
  Mechanisms underlying immunodeficiency caused by Vitamin A deprivation.
  
• Holland, Eric C.
  Cancer Biology and Genetics
  Molecular mechanisms underlying the pathogenesis of CNS tumors and modeling of these cancers in the mouse.
  
• Houghton, Alan N.
  Immunology
  The immune response to cancer, immune recognition of self and mutated molecules; development of new immunotherapies.
  
• Hricak, Hedvig
  Radiology
  Methodologies of molecular imaging of prostate and gynecologic tumors.
  
• Hurwitz, Jerard
  Molecular Biology
  Mechanisms of eukaryotic DNA replication and the isolation and characterization of the proteins involved.
  
• Huse, Morgan
  Immunology
  The study of intracellular signaling dynamics in lymphocytes.
  

I

J

• Jallepalli, Prasad V.
  Molecular Biology
  Mechanisms of high-fidelity chromosome segregation in human cells.
  
• Jasin, Maria
  Developmental Biology
  Double-strand break repair and genomic integrity in mammalian cells and the relationship to tumor suppression.
  
• Jiang, Xuejun
  Cell Biology
  Programmed cell death, molecular mechanisms, and its roles in tumorigenesis.
  
• Joyce, Johanna
  Cancer Biology and Genetics
  Understanding how a tumor cell co-opts its environment to promote its growth and progression.
  
• Joyner, Alexandra L.
  Developmental Biology
  Genetic and cellular regulation of neural development and adult stem cell biology.
  

K

• Kaltschmidt, Julia A.
  Developmental Biology
  Understanding the mechanisms of synaptic specificity underlying neuronal circuit formation
  
• Keeney, Scott N.
  Molecular Biology
  Molecular mechanisms of the initiation of meiotic recombination.
  
• Kelly, Thomas J.
  Molecular Biology
  Regulatory mechanisms that control DNA replication during the cell cycle of eukaryotic cells.
  
• Kenney, Anna Marie
  Cancer Biology and Genetics
  Signaling pathways regulating proliferation in brain development and cancer.
  
• Klein, Robert J.
  Cancer Biology and Genetics
  Identification of genes responsible for inherited predisposition to cancer.
  
• Koff, Andrew
  Molecular Biology
  The role of cell cycle inhibitors in differentiation and how their loss affects tumorigenesis.
  
• Kolesnick, Richard N.
  Molecular Pharmacology and Chemistry
  The role of ceramide signaling in radiation-induced vascular dysfunction and tumor regression.
  
• Koutcher, Jason A.
  Medicine
  The application of magnetic resonance spectroscopy and imaging to enhancing the therapeutic gain of different anti-neoplastic modalities.
  

L

• Lacy, Elizabeth H.
  Developmental Biology
  Mechanisms of gastrulation and organogenesis during mouse development.
  
• Ladanyi, Marc
  Human Oncology and Pathogenesis
  Molecular pathogenesis of human translocation-associated sarcomas.
  
• Lai, Eric
  Developmental Biology
  Control of developmental patterning by Notch signaling and micro RNAs.
  
• Larson, Steven M.
  Molecular Pharmacology and Chemistry
  Molecular imaging in animals and humans using high-resolution diagnostic instruments, such as Positron Emission Tomography, and Single Photon Emission Tomography.
  
• Leslie, Christina
  Computational Biology
  Machine learning algorithms for computational and systems biology.
  
• Levine, Ross L.
  Human Oncology and Pathogenesis
  Investigation of genetic basis of hematopoietic malignancies.
  
• Lewis, Jason S.
  Molecular Pharmacology and Chemistry
  Development of radiopharmaceuticals for the imaging and therapy of cancer.
  
• Li, Ming
  Immunology
  Mechanisms of T Cell homeostasis, tolerance, and immunity, and their relevance to autoimmune diseases and cancer.
  
• Li, Yueming
  Molecular Pharmacology and Chemistry
  Function and regulation of transmembrane proteases and development of novel protease-based cancer therapies.
  
• Lima, Christopher D.
  Structural Biology
  Structural biology of post-translational protein modification and RNA processing.
  
• Liu, Jidong
  Cell Biology
  Molecular mechanism of RNA interference, function, and regulation of mammalian cytoplasmic processing bodies.
  
• Livingston, Philip O.
  Medicine
  Tumor vaccinology, approaches to augmenting the antibody and T cell response to defined cancer antigens.
  
• Long, Stephen B.
  Structural Biology
  Structural biology of ion channels and enzymatic membrane proteins.
  

M

• Marians, Kenneth J.
  Molecular Biology
  Mechanisms of replication restart and chromosome segregation.
  
• Massagué, Joan
  Cancer Biology and Genetics
  Control of cell growth and phenotype; delineating the mechanisms of relevance to tumor progression, metastasis, and response to therapy.
  
• Mellinghoff, Ingo K.
  Human Oncology and Pathogenesis
  Molecular determinants in drug response and growth factor signaling.
  
• Michor, Franziska
  Computational Biology
  Theoretical evolutionary biology of cancer initiation and progression, treatment and resistance.
  
• Moore, Malcolm A.S.
  Cell Biology
  The biology of the hematopoietic stem cell in normal and malignant lympho-hematopoiesis.
  

N

• Nikolov, Dimitar B.
  Structural Biology
  Structural, biophsyical, and biochemical characterization of the molecular mechanisms of cell-cell interactions and signal transduction in the nervous system.
  
• Nimer, Stephen D.
  Molecular Pharmacology and Chemistry
  Defining the molecular and biological abnormalities, and the underlying transcriptional regulation mechanisms involved in the development and growth of hematologic cancers.
  

O

• O'Reilly, Richard J.
  Immunology
  Genetic disparities and cellular interactions between donor and host that affect allogeneic hematopoietic cell transplantation.
  
• Offit, Kenneth
  Medicine
  Cancer genetics: gene characterization, genetic/epidemiologic studies of cancer-predisposing alleles, and the therapeutic, prognostic, and psychosocial translation of these findings.
  

P

• Pamer, Eric G.
  Immunology
  T cell and innate inflammatory responses to bacterial and fungal infections.
  
• Pao, William
  Human Oncology and Pathogenesis
  Lung cancer; lung tumorigenesis.
  
• Pasternak, Gavril W.
  Molecular Pharmacology and Chemistry
  Molecular mechanisms of opioid receptor actions, analgesics, and G-protein-coupled receptors.
  
• Patel, Dinshaw
  Structural Biology
  Structural biology of macromolecular recognition: RNA catalysis, RNA interference, and bypass of DNA damage.
  
• Pavletich, Nikola P.
  Structural Biology
  Structural biology of oncogenes and tumor suppressors.
  
• Petrini, John H.J.
  Molecular Biology
  Repair of chromosomal breaks and the activation of the DNA damage-induced cell cycle checkpoints.
  
• Ptashne, Mark S.
  Molecular Biology
  Mechanisms of gene regulation.
  

Q

R

• Resh, Marilyn
  Cell Biology
  Regulation of protein function by fatty acylation; mechanism of retroviral particle assembly; and mechanisms of normal and malignant glial cell growth.
  
• Rosen, Neal
  Molecular Pharmacology and Chemistry
  Understanding biochemical mechanisms underlying phenotypes caused by tyrosine kinase activation in epithelial tumors and the development of new therapeutic strategies.
  

S

• Sadelain, Michel
  Molecular Pharmacology and Chemistry
  Mechanisms governing transgene expression, stem cell engineering, and genetic strategies to enhance immunity against cancer.
  
• Sander, Chris
  Computational Biology
  Using computational biology to analyze and simulate biological processes at different levels of organization.
  
• Sant'Angelo, Derek B.
  Immunology
  Genetic pathways that govern positive selection of T cells in the thymus.
  
• Sawyers, Charles L.
  Human Oncology and Pathogenesis
  Molecularly targeted cancer therapy.
  
• Scheinberg, David A.
  Molecular Pharmacology and Chemistry
  Discovery and development of novel, specific immunotherapeutic agents and targeted nanodevices for cancer therapy.
  
• Schwartz, Gary K.
  Medicine
  Identification of cell cycle inhibitors which promote chemotherapy induced apoptosis and their use in cancer therapy.
  
• Shi, Songhai
  Developmental Biology
  Molecular and cellular mechanisms underlying mammalian neuronal development and circuit formation.
  
• Shuman, Stewart
  Molecular Biology
  Mechanisms and structures of the mRNA cap-forming enzymes and the means by which capping is coupled to transcription.
  
• Singer, Sam
  Surgery
  Development of a novel clinically relevant biochemical and molecular system of prognostic determinants for soft tissue sarcoma.
  
• Solit, David
  Human Oncology and Pathogenesis Program
  Human oncology and pathogenesis, genomics, oncogenes and tumor suppressors, cancer therapeutics, and clinical trials.
  
• Spriggs, David R.
  Medicine
  Molecular mechanisms of drug resistance in ovarian cancer.
  
• Studer, Lorenz P.
  Developmental Biology
  Stem cells as tool to understand normal and pathological development in the CNS and to develop cell based strategies for neural repair.
  

T

• Tan, Derek S.
  Molecular Pharmacology and Chemistry
  Diversity-oriented synthesis and rational design for cancer chemical biology and drug discovery.
  
• Tempst, Paul J.
  Molecular Biology
  Development of proteomic technologies and approaches for studying the eukaryotic transcriptional machineries and for cancer biomarker discovery.
  
• Tsou, Meng-Fu Bryan
  Cell Biology
  Cell Cycle control of centrosome duplication and degeneration.
  

U

V

• van den Brink, Marcel
  Immunology
  Immunology of bone marrow transplantation.
  
• Varmus, Harold
  Cancer Biology and Genetics
  Molecular mechanisms of oncogenesis; mouse models. The Wnt signaling pathways, and human lung cancer.
  
• Vilar, Jose
  Computational Biology
  Computational modeling of biological processes at the molecular, cellular, and population levels of organization.
  

W

• Weinstein, Harel
  Computational Biology
  Structural, dynamic and integrative determinants of molecular and cellular mechanisms underlying physiological function and pharmacological activity.
  
• Wendel, Hans-Guido
  Cancer Biology and Genetics
  Modeling the genetics of tumor initiation, progression, and treatment response in vivo.
  

X

Y

• Young, James W.
  Medicine
  Innate and adaptive immunity against tumors and viruses stimulated by human dendritic cells.
  

Z

• Zallen, Jennifer A.
  Developmental Biology
  Generation of tissue structure through the collective action of cell populations.
  
• Zhao, Xiaolan
  Molecular Biology
  Chromosomal organization and function; role of sumoylation in chromosomal metabolism.