Bexxar regimen
(BEK-sar REH-jih-men)
A combination of drugs used to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the treatment of other types of cancer. Bexxar regimen is made up of a monoclonal antibody called tositumomab and a form of tositumomab that is linked to a radioactive substance called iodine I 131. It is a type of radioimmunoconjugate. Also called Bexxar and tositumomab and iodine I 131 tositumomab.
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antibody (AN-tee-BAH-dee)
A protein made by plasma cells (a type of white blood cell) in response to an antigen (a substance that causes the body to make a specific immune response). Each antibody can bind to only one specific antigen. The purpose of this binding is to help destroy the antigen. Some antibodies destroy antigens directly. Others make it easier for white blood cells to destroy the antigen.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
Bexxar (BEK-sar)
A combination of drugs used to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the treatment of other types of cancer. Bexxar is made up of a monoclonal antibody called tositumomab and a form of tositumomab that is linked to a radioactive substance called iodine I 131. It is a type of radioimmunoconjugate. Also called Bexxar regimen and tositumomab and iodine I 131 tositumomab.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
cancer (KAN-ser)
A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
iodine (I-oh-dine)
An element that is necessary for the body to make thyroid hormone. It is found in shellfish and iodized salt.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
iodine I 131 tositumomab (I-oh-dine I 131 TAH-sih-TOO-moh-mab)
A drug used with another drug to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the treatment of other types of cancer. Iodine I 131 tositumomab is a form of the monoclonal antibody tositumomab that is linked to the radioactive substance iodine I 131. It is a type of radioimmunoconjugate.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
lymphoma (lim-FOH-muh)
Cancer that begins in cells of the immune system. There are two basic categories of lymphomas. One kind is Hodgkin lymphoma, which is marked by the presence of a type of cell called the Reed-Sternberg cell. The other category is non-Hodgkin lymphomas, which includes a large, diverse group of cancers of immune system cells. Non-Hodgkin lymphomas can be further divided into cancers that have an indolent (slow-growing) course and those that have an aggressive (fast-growing) course. These subtypes behave and respond to treatment differently. Both Hodgkin and non-Hodgkin lymphomas can occur in children and adults, and prognosis and treatment depend on the stage and the type of cancer.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
radioactive (RAY-dee-oh-AK-tiv)
Giving off radiation.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
regimen (REH-jih-men)
A treatment plan that specifies the dosage, the schedule, and the duration of treatment.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
tositumomab (TAH-sih-TOO-moh-mab)
A drug used together with another drug to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the treatment of other types of cancer. Tositumomab binds to a protein called CD20, which is found on the surface of B cells, and may kill cancer cells. It is a type of monoclonal antibody.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
(http://www.cancer.gov/dictionary)
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