dexrazoxane hydrochloride
(DEX-ruh-ZOK-sane HY-droh-KLOR-ide)
A drug used to treat severe side effects caused by certain anticancer drugs. It is used under the brand name Totect to treat the toxic effects of an anticancer drug that leaks from a vein into surrounding tissue and causes tissue damage. It is also used under the brand name Zinecard to reduce heart damage in women given doxorubicin for breast cancer that has spread. Dexrazoxane hydrochloride is also being studied in the treatment of cancer. It is a type of cardioprotective agent, a type of chemoprotective agent, and a type of topoisomerase inhibitor.
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breast (brest)
Glandular organ located on the chest. The breast is made up of connective tissue, fat, and breast tissue that contains the glands that can make milk. Also called mammary gland.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
cancer (KAN-ser)
A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
chemoprotective (KEE-moh-proh-TEK-tiv)
A quality of some drugs used in cancer treatment. Chemoprotective agents protect healthy tissue from the toxic effects of anticancer drugs.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
dexrazoxane (DEX-ruh-ZOK-sane)
The active ingredient in a drug used to treat severe side effects caused by certain anticancer drugs. Under the brand name Totect it is used to treat the toxic effects of an anticancer drug that leaks from a vein into surrounding tissue and causes tissue damage. Under the brand name Zinecard it is used to reduce heart damage in women given doxorubicin for breast cancer that has spread. Dexrazoxane is also being studied in the treatment of cancer. It is a type of cardioprotective agent, a type of chemoprotective agent, and a type of topoisomerase inhibitor.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
doxorubicin (DOK-soh-ROO-bih-sin)
A drug that is used to treat many types of cancer and is being studied in the treatment of other types of cancer. Doxorubicin comes from the bacterium . It damages DNA and may kill cancer cells. It is a type of anthracycline antitumor antibiotic. Also called Adriamycin PFS, Adriamycin RDF, doxorubicin hydrochloride, hydroxydaunorubicin, and Rubex.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
drug (drug)
Any substance, other than food, that is used to prevent, diagnose, treat or relieve symptoms of a disease or abnormal condition. Also refers to a substance that alters mood or body function, or that can be habit-forming or addictive, especially a narcotic.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
tissue (TIH-shoo)
A group or layer of cells that work together to perform a specific function.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
topoisomerase inhibitor (TOH-poh-i-SAH-meh-rays in-HIH-bih-ter)
A substance that blocks topoisomerases (enzymes that break and rejoin DNA strands and are needed for cells to divide and grow). Blocking these enzymes may kill cancer cells. Certain topoisomerase inhibitors are being studied in the treatment of cancer.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
Totect (TOH-tekt)
A drug used to treat the toxic effects of an anticancer drug that leaks from a vein into surrounding tissue and causes tissue damage. It is also being studied in the treatment of cancer. Totect contains the active ingredient dexrazoxane. It is a type of chemoprotective agent, a type of cardioprotective agent, and a type of topoisomerase inhibitor.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
toxic (TOK-sik)
Having to do with poison or something harmful to the body. Toxic substances usually cause unwanted side effects.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
vein (vayn)
A blood vessel that carries blood to the heart from tissues and organs in the body.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
Zinecard (ZIH-neh-kard)
A drug used to reduce heart damage in women given doxorubicin for breast cancer that has spread. It is also being studied in the treatment of cancer. Zinecard contains the active ingredient dexrazoxane. It is a type of cardioprotective agent, a type of chemoprotective agent, and a type of topoisomerase inhibitor.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
Source: The National Cancer Institute's Dictionary of Cancer Terms
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(http://www.cancer.gov/dictionary)
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