A
drug used to relieve certain side effects caused by treatment with opiods (pain killers similar to morphine), such as
constipation (hard, dry stools), itching, and low
urine flow.
Relistor binds to
opioid receptors outside the brain and may block the side effects of opioid drugs without affecting their ability to relieve pain. Relistor is a type of peripheral opioid
receptor antagonist. Also called
methylnaltrexone bromide.
antagonist (an-TA-guh-nist)
In medicine, a substance that stops the action or effect of another substance. For example, a drug that blocks the stimulating effect of estrogen on a tumor cell is called an estrogen receptor antagonist.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
constipation (KON-stih-PAY-shun)
A condition in which stool becomes hard, dry, and difficult to pass, and bowel movements don’t happen very often. Other symptoms may include painful bowel movements, and feeling bloated, uncomfortable, and sluggish.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
drug (drug)
Any substance, other than food, that is used to prevent, diagnose, treat or relieve symptoms of a disease or abnormal condition. Also refers to a substance that alters mood or body function, or that can be habit-forming or addictive, especially a narcotic.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
methylnaltrexone (MEH-thul-nal-TREK-sone)
The active ingredient in a drug used to relieve certain side effects caused by treatment with opiods (pain killers similar to morphine), such as constipation (hard, dry stools), itching, and low urine flow. Methylnaltrexone binds to opioid receptors outside the brain and may block the side effects of opioid drugs without affecting their ability to relieve pain. Methylnaltrexone is a type of peripheral opioid receptor antagonist.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
opioid (OH-pee-OYD)
A substance used to treat moderate to severe pain. Opioids are like opiates, such as morphine and codeine, but are not made from opium. Opioids bind to opioid receptors in the central nervous system. Opioids used to be called narcotics. An opioid is a type of alkaloid.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
receptor (reh-SEP-ter)
A molecule inside or on the surface of a cell that binds to a specific substance and causes a specific physiologic effect in the cell.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
Relistor (REH-lih-stor)
A drug used to relieve certain side effects caused by treatment with opiods (pain killers similar to morphine), such as constipation (hard, dry stools), itching, and low urine flow. Relistor binds to opioid receptors outside the brain and may block the side effects of opioid drugs without affecting their ability to relieve pain. Relistor is a type of peripheral opioid receptor antagonist. Also called methylnaltrexone bromide.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
urine (YOOR-in)
Fluid containing water and waste products. Urine is made by the kidneys, stored in the bladder, and leaves the body through the urethra.
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)