Tasigna
(tuh-SIG-nuh)
A drug used to treat certain types of chronic myelogenous leukemia (CML). It is used in some newly diagnosed patients. It is also used in patients who have not gotten better after treatment with other anticancer drugs or who are not able to take imatinib mesylate. It is also being studied in the treatment of other types of cancer. Tasigna blocks a protein called BCR-ABL, which may help keep cancer cells from growing. It is a type of tyrosine kinase inhibitor. Also called nilotinib.
(http://www.cancer.gov/dictionary)
(http://www.cancer.gov/dictionary)
(http://www.cancer.gov/dictionary)
(http://www.cancer.gov/dictionary)
(http://www.cancer.gov/dictionary)
(http://www.cancer.gov/dictionary)
(http://www.cancer.gov/dictionary)
(http://www.cancer.gov/dictionary)
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(http://www.cancer.gov/dictionary)
cancer (KAN-ser)
A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
chronic (KRAH-nik)
A disease or condition that persists or progresses over a long period of time.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
drug (drug)
Any substance, other than food, that is used to prevent, diagnose, treat or relieve symptoms of a disease or abnormal condition. Also refers to a substance that alters mood or body function, or that can be habit-forming or addictive, especially a narcotic.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
imatinib mesylate (ih-MA-tih-nib MEH-zih-layt)
A drug used to treat different types of leukemia and other cancers of the blood, gastrointestinal stromal tumors, skin tumors called dermatofibrosarcoma protuberans, and a rare condition called systemic mastocytosis. It is also being studied in the treatment of other types of cancer. Imatinib mesylate blocks the protein made by the bcr/abl oncogene. It is a type of tyrosine kinase inhibitor. Also called Gleevec and STI571.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
kinase (KY-nays)
A type of enzyme that causes other molecules in the cell to become active. Some kinases work by adding chemicals called phosphates to other molecules, such as sugars or proteins. Kinases are a part of many cell processes. Some cancer treatments target certain kinases that are linked to cancer.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
leukemia (loo-KEE-mee-uh)
Cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
myelogenous (MY-eh-LAH-jeh-nus)
Having to do with, produced by, or resembling the bone marrow. Sometimes used as a synonym for myeloid; for example, acute myeloid leukemia and acute myelogenous leukemia are the same disease.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
nilotinib (ny-LOH-tih-nib)
A drug used to treat certain types of chronic myelogenous leukemia (CML). It is used in some newly diagnosed patients. It is also used in patients who have not gotten better after treatment with other anticancer drugs or who are not able to take imatinib mesylate. It is also being studied in the treatment of other types of cancer. Nilotinib blocks a protein called BCR-ABL, which may help keep cancer cells from growing. It is a type of tyrosine kinase inhibitor. Also called Tasigna.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
protein (PROH-teen)
A molecule made up of amino acids that are needed for the body to function properly. Proteins are the basis of body structures such as skin and hair and of substances such as enzymes, cytokines, and antibodies.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
Tasigna (tuh-SIG-nuh)
A drug used to treat certain types of chronic myelogenous leukemia (CML). It is used in some newly diagnosed patients. It is also used in patients who have not gotten better after treatment with other anticancer drugs or who are not able to take imatinib mesylate. It is also being studied in the treatment of other types of cancer. Tasigna blocks a protein called BCR-ABL, which may help keep cancer cells from growing. It is a type of tyrosine kinase inhibitor. Also called nilotinib.
Source: The National Cancer Institute's Dictionary of Cancer Terms(http://www.cancer.gov/dictionary)
Source: The National Cancer Institute's Dictionary of Cancer Terms
(http://www.cancer.gov/dictionary)
(http://www.cancer.gov/dictionary)
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