Major Research Areas
Developmental Biology
Carmena, A. and Baylies, M.K. The PDZ protein Canoe/AF-6 links RAS-MAPK, Notch and Wingless/Wnt signaling pathways by directly interacting RAS, Notch and Dishevelled. PLoS ONE 2006 e66

Beckett, K and Baylies, M.K. "The Development of the Drosophila larval body wall muscles" In: The Fly Neuromuscular Junction: Structure and Function, International Review of Neurobiology, V 75 (Budnik, Ruiz-Canada, eds), San Diego, Elsevier Academic Press. P 55-70.

Llorens, J., Navarro, J, Martinez-Sebastian, M., Baylies, MK., Schneuwly, S, Botella, J and Molto, M. Causative Role of oxidative stress in a Drosophila model of Friedreich ataxia. FASEB 2006

Beckett K., Baylies M.K. Parcas, a regulator of non-receptor tyrosine kinase signaling, acts during anterior-posterior patterning and somatic muscle development in Drosophila melanogaster. Developmental Biology 2006 299:176-92.

Carmena, A., and Baylies, M.K. The Development of the Drosophila Larval Somatic Musculature in "Drosophila Muscle Development". Editor: H. Sink Landes Press. 2005

Cox, V., Beckett K. and Baylies, M.K. Delivery of Wingless to the Ventral Mesoderm by the developing Central Nervous System ensures proper patterning of individual Slouch-positive muscle progenitors. Developmental Biology 2005 287: 403-415.

Cox,V., Baylies, MK. Specification of individual Slouch muscle progenitors in Drosophila requires sequential Wingless signaling. Development 2005 132: 713-724.

Tapanes-Castillo,A. and Baylies, M.K. Notch signaling directs the patterning of mesodermal segments in Drosophila by regulating a bHLH transcription factor network. Development 2004 131:2359-2372.

Artero, R., Furlong, E., Beckett, K., Scott, M. and Baylies, M.K. Notch and Ras signaling pathway effector genes expressed in fusioncompetent and founder cels during Drosophila myogenesis. Development 2003 130(25): 627-72.

Carmena, A., Buff, E., Jiménez, F., Baylies, M.K.* and Michelson, A.* Ras and Notch signaling pathways interact to generate specific cell fates during Drosophila mesoderm differentiation. Developmental Biology 2002, 244(2):226-42. (* joint senior authors)

Castanon, I., Von Stetina, S, Kass, J and Baylies, M.K. Dimerization partners determine Twist activity during Drosophila myogenesis. Development 2001 128, 3145-3159

Artero, R., Castanon, I., and Baylies, M.K.The immunoglobulin like protein Hibris functions as a dose-dependent regulator of myoblast fusion and is differentially controlled by Ras and Notch signalling. Development 2001; 128: 4251-64.

Halfon, M., Carmena,A., Gisselbrecht, S., Sackerson, C., Jimenez, F., Baylies, M., and Michelson,A. Ras pathway specificity is determined by the integration of multiple signal-activated and tissue restricted transcription factors. Cell 2000, 103, 63-74.

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