Major Research Areas

Selected Publications

Serve H, Yee NS, Stella G, Sepp-Lorenzino L, Tan JC, Besmer P. Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell-adhesion in mast cells. EMBO J. 1995;14:473-483.

Vosseller K, Stella G, Yee NS, Besmer P. c-kit receptor signaling through phosphatidylinositide-3'-kinase-binding site and protein kinase C: role in mast cell enhancement of degranulation, adhesion, and membrane ruffling. Mol Biol Cell. 1997;8:909-922.

Timokhina I, Kissel H, Stella G, Besmer P. Kit signaling through PI3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation. EMBO J. 1998;17:6250-6262.

Kissel H, Timokhina I, Hardy MP, Rothschild G, Tajima Y, Soares V, Angeles M, Whitlow SR, Manova M, Besmer P. Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signalling in spermatogenesis and oogenesis without affecting other kit responses. EMBO J. 2000;19:1312-1326.

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