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Jerard Hurwitz
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Stewart Shuman
Publications
Changela A, Ho CK, Martins A, Shuman S, Mondragon A. (2001) Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme. EMBO J. 2001;20:2575-2586.
Krogh BO, Shuman S. (2002) A poxvirus-like type IB topoisomerase family in bacteria. Proc Natl Acad Sci USA. 2002;99:1853-1858.
Ho CK, Shuman S. (2001) A yeast-like mRNA capping apparatus in Plasmodium falciparum. Proc Natl Acad Sci USA. 2001;98:3050-3055.
Jankowsky E, Gross CH, Shuman S, Pyle AM. (2001) Active disruption of an RNA-protein interaction by a DExH/D RNA helicase. Science. 2001;291:121-125.
Odell M, Sriskanda V, Shuman S, Nikolov DB. (2000) Crystal structure of eukaryotic DNA ligase-adenylate illuminates the mechanism of nick sensing and strand joining. Mol Cell. 2000;6:1183-1193.
Schroeder SC, Schwer B, Shuman S, Bentley D. (2000) Dynamic association of capping enzymes with transcribing RNA polymerase II. Genes Dev. 2000;14:2435-2440.
Krogh BO, Shuman S. (2000) Catalytic mechanism of DNA topoisomerase IB. Mol Cell. 2000;5:1035-1041.
Jankowsky E, Gross CH, Shuman S, Pyle AM. (2000) The DExH protein NPH-II is a processive and directional motor for unwinding RNA. Nature. 2000;403:447-451.
Lima CD, Wang LK, Shuman S. (1999) Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus. Cell. 1999;99:533-543.
Ho CK, Shuman S. (1999) Distinct roles for CTD Ser2 and Ser5 phosphorylation in the recruitment and allosteric activation of mammalian capping enzyme. Mol Cell. 1999;3:405-411.
Shuman S. (1998) Polynucleotide ligase activity of eukaryotic topoisomerase I. Mol Cell. 1998;1:741-748.
Cheng C, Kussie P, Pavletich N, Shuman S. (1998) Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases. Cell. 1998;92:841-850.
Deng L, Shuman S. (1998) Vaccinia NPH-I, a DExH-box ATPase, is the energy coupling factor for mRNA transcription termination. Genes Dev. 1998;12:538-546.
Hakansson K, Doherty AJ, Shuman S, Wigley DB. (1997) X-ray crystallography reveals a large conformational change during guanyl transfer by mRNA capping enzymes. Cell. 1997;89:545-553.
Shuman S, Bear DG, Sekiguchi J. (1997) Intramolecular synapsis of duplex DNA by vaccinia topoisomerase. EMBO J. 1997;16:6584-6589.
Wang SP, Deng L, Ho CK, Shuman S. (1997) Phylogeny of mRNA capping enzymes. Proc Natl Acad Sci USA. 1997;94:9573-9578.
Sekiguchi J, Shuman S. (1997) Site-specific ribonuclease activity of eukaryotic topoisomerase I. Mol Cell. 1997;1:89-97.
Shuman S. (1997) Origins of mRNA identity: capping enzymes bind to the phosphorylated C-terminal domain of RNA polymerase II. Proc Natl Acad Sci USA. 1997;94:12758-12760.
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