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David Allis @ Rockefeller.edu
Jerard Hurwitz
Prasad Jallepalli
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Stewart Shuman
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DNA Damage Recognition and Repair by DNA Ligases
Selected Publications
Sriskanda V, Shuman S. (1998) Specificity and fidelity of strand joining by Chlorella virus DNA ligase. Nucleic Acids Res. 1998;26:3536-3541.
Sriskanda V, Shuman S. (2002) Role of nucleotidyl transferase motif V in strand joining by Chlorella virus DNA ligase. J Biol Chem. 2002;277:9661-9667.
Sriskanda V, Shuman S. (2002) Role of nucleotidyl transferase motifs I, III and IV in the catalysis of phosphodiester bond formation by Chlorella virus DNA ligase. Nucleic Acids Res. 2002;30:903-911.
Sriskanda V, Shuman S. (2001) A second NAD+-dependent DNA ligase (LigB) in Escherichia coli. Nucleic Acids Res. 2001 Dec 15;29(24):4930-4.
Sriskanda V, Moyer RW, Shuman S. (2001) NAD+-dependent DNA ligase encoded by a eukaryotic virus. J Biol Chem. 2001;276:36100-36109.
Odell M, Sriskanda V, Shuman S, Nikolov DB. (2000) Crystal structure of eukaryotic DNA ligase-adenylate illuminates the mechanism of nick sensing and strand joining. Mol Cell. 2000;6:1183-1193.
Sriskanda V, Kelman Z, Hurwitz J, Shuman S. (2000) Characterization of an ATP-dependent DNA ligase from the thermophilic archaeon Methanobacterium thermoautotrophicum. Nucleic Acids Res. 2000;28:2221-2228.
Odell M, Shuman S. (1999) Footprinting of Chlorella virus DNA ligase bound at a nick in duplex DNA. J Biol Chem. 1999;274:14032-14039.
Sriskanda V, Shuman S. (2002) Conserved residues in domain Ia are required for the reaction of Escherichia coli DNA ligase with NAD+. J Biol Chem. 2002;277:9695-9700.
Sriskanda V, Shuman S. (1988) Mutational analysis of Chlorella virus DNA ligase: catalytic roles of domain I and motif VI. J Biol Chem. 2002;277:9695-9700.
Shuman S, Ru XM. (1995) Mutational analysis of vaccinia DNA ligase defines residues essential for covalent catalysis. Virology. 1995;211:73-83.
Sriskanda V, Shuman S. (1998) Chlorella virus DNA ligase: nick recognition and mutational analysis. Nucleic Acids Res. 1998;26:525-531.
Sekiguchi J, Shuman S. (1997) Nick sensing by DNA ligase requires a 5' phosphate at the nick and occupancy of the adenylate binding site on the enzyme. J Virol. 1997;71:9679-9684.
Sekiguchi J, Shuman S. (1997) Ligation of RNA-containing duplexes by vaccinia DNA ligase. Biochemistry. 1997;36:9073-9079.
Cheng C, Shuman S. (1997) Characterization of an ATP-dependent DNA ligase encoded by Haemophilus influenzae. Nucleic Acids Res. 1997;25:1369-1374.
Ho CK, Van Etten JL, Shuman S. (1997) Characterization of an ATP-dependent DNA ligase encoded by Chlorella virus PBCV-1. J Virol. 1997;71:1931-1937.
Sekiguchi J, Shuman S. (1997) Domain structure of vaccinia DNA ligase. Nucleic Acids Res. 1997;25:727-734.
Shuman S. (1996) Closing the gap on DNA ligase. Structure. 1996;4:653-656.
Shuman S. (1995) Vaccinia DNA ligase: specificity, fidelity, and inhibition. Biochemistry. 1995;34:16138-16147.
Sriskanda V, Schwer B, Ho CK, Shuman S. (1999) Mutational analysis of Escherichia coli DNA ligase identifies amino acids required for nick-ligation in vitro and for in vivo complementation of the growth of yeast cells deleted for CDC9 and LIG4. Nucleic Acids Res. 1999;27:3953-3963.
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DNA Damage Recognition and Repair by DNA Ligases
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