Research Programs Cancer Biology & Genetics Cell Biology Raju Chaganti Hironori Funabiki @ Rockefeller.edu Filippo Giancotti Alan Hall Xuejun Jiang Jidong Liu Paul A. Marks Malcolm Moore Marilyn Resh Urs Rutishauser Timothy A. Ryan @ Cornell.edu Meng-Fu Bryan Tsou Computational Biology Developmental Biology Immunology Molecular Biology Molecular Pharmacology & Chemistry Structural Biology Postdoctoral Training Graduate Education Summer Undergraduate Research Program Core Facilities Collaborative Research Centers Sloan-Kettering Institute > Research Programs > Cell Biology > Raju Chaganti Publications Dyomin VG, Palanisamy N, Lloyd KO, Dyomina K, Jhanwar SC, Houldsworth J, Chaganti RSK. MUC1 is activated in a B-cell lymphoma by the t(1;14)(q21;q32) translocation and is rearranged and amplified in B-cell lymphoma subsets. Blood. 2000;2661-2671. Chang CC, Ye BH, Chaganti RSK, Dalla-Favera R. BCL-6, a POZ/Zinc-finger protein, is a sequence-specific transcriptional repressor. Proc Natl Acad Sci USA. 1996;6947-6952. Edelmann W, Cohen PE, Kane M, Lau K, Morrow B, Bennett S, Umar A, Kunkel T, Cattoretti G, Chaganti R, Pollard JW, Kolodner RD, and Kucherlapati, R. Meiotic pachytene arrest in MLH1-deficient mice. Cell. 1996;1125-1134. Houldsworth J, Mathew S, Rao P, Dyomina K, Louie DC, Parsa N, Offit K, Chaganti RSK. REL proto-oncogene is frequently amplified in extranodal diffuse large cell lymphoma. Blood. 1996;25-29. Iida S, Rao PH, Nallasivam P, Hibshoosh H, Butler M, Louie DC, Dyomin V, Ohno H, Chaganti RSK, Dalla-Favera R. The t(9;14)(p13;q32) chromosomal translocation associated with lymphoplasmacytoid lymphomas involves the PAX-5 gene. Blood. 1996;4110-4117. Murty VV, Renault B, Falk CT, Bosl GJ, Kucherlapati R, Chaganti RSK. Physical mapping of a commonly deleted region, the site of a candidate tumor suppressor gene, at 12q22 in human male germ cell tumors. Genomics. 1996;562-570. Dyomin VG, Rao PH, Dalla-Favera R, Chaganti RSK. BCL8, a novel gene involved in translocations affecting band 15q11-13 in diffuse large-cell lymphoma. Proc Natl Acad Sci USA. 1997;5728-5732. Houldsworth J, Reuter V, Bosl JG, Chaganti RS. Aberrant expression of cyclin D2 is an early event in human male germ cell tumorigenesis. Cell Growth Differ. 1997;239-299. Iida S, Rao PH, Butler M, Corradini P, Boccadoro M, Klein B, Chaganti, RSK, Dalla-Favera R. Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma. Nature Genet. 1997;226-230. Chen W, Butler M, Rao PH, Chaganti SR, Louie DC, Dalla-Favera R, Chaganti RSK. The t(2;3)(q21;q27) translocation in non-Hodgkin's lymphoma displays BCL6 mutations in the 5' regulatory region and chromosomal breakpoints distant from the gene. Oncogene. 1998;1717-1722. Chaganti SR, Rao PH, Chen W, Dyomin V, Jhanwar SC, Parsa NZ, Dalla-Favera R, Chaganti RSK. Deregulation of BCL6 in non-Hodgkin lymphoma by insertion of IGH sequences in complex translocations involving band 3q27. Genes Chromosomes Cancer. 1998;328-336. Ye BH, Cattoretti G, Shen Q, Zhang J, Hawe N, de Waard R, Leung C, Nouri-Shirazi M, Orazi A, Chaganti RSK, Rothman P, Stall AM, Pandolfi PP, Dalla-Favera R. The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nature Genet. 1997;161-170. Chen W, Iida S, Louie DC, Dalla-Favera R, Chaganti RSK. Heterologous promoters fused to BCL6 by chromosomal translocations affecting band 3q27 cause its deregulated expression during B-cell differentiation. Blood. 1998;603-607. Cigudosa JC, Rao PH, Calasanz JM, Odero MD, Michaeli J, Jhanwar SC, Chaganti RS. Characterization of nonrandom chromosomal gains and losses in multiple myeloma by comparative genomic hybridization. Blood. 1998;3007-3010. Pasqualucci L, Migliazza A, Fracchiolla N, Williams C, Neri A, Baldini L, Chaganti RSK, Klein U, Küppers R, Jajewsky K, Dalla-Favera R. BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci. Proc Natl Acad Sci USA. 1998;11816-11821. Rao PH, Houldsworth J, Dyomina K, Parsa NZ, Cigudosa JC, Louie DC, Popplewell L, Offit K, Jhanwar SC, Chaganti RSK. Chromosomal and gene amplification in diffuse large B-cell lymphoma. Blood. 199;234-240. Rao PH, Houldsworth J, Palanisamy N, Murty VV, Reuter VE, Motzer RJ, Bosl GJ, Chaganti RS. Chromosomal amplification is associated with cisplatin resistance of human male germ cell tumors. Cancer Res. 1998; 4260-4263. Cigudosa JC, Parsa NZ, Jhanwar SC, Johansson B, Mitelman F, Chaganti RSK. Cytogenetic analysis of 363 consecutively ascertained diffuse large B-cell lymphomas. Genes Chromosomes Cancer. 1999;123-133. Fakruddin M, Chaganti RSK, Murty VVVS. Lack of BCL10 mutations in germ cell tumors and B cell lymphomas. Cell. 1999;683-684. Murty VV, Montgomery K, Dutta S, Bala S, Renault B, Bosl GJ, Kucherlapati R, Chaganti RS. A 3-Mb high-resolution BAC/PAC contig of 12q22 encompassing the 830-kb consensus minimal deletion in male germ cell tumors. Genome Res. 1999;662-671. Chaganti RSK, Houldsworth J. Genetics and biology of adult human male germ cell tumors. Cancer Res. 2000;1475-1482. Ye BH, Chaganti S, Chang CC, Niu H, Corradini P, Chaganti RSK, Dalla-Favera R. Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma. EMBO J. 1995;6209-6217.

Memorial Sloan-Kettering Cancer Center | Sloan-Kettering Institute Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan-Kettering Cancer Center

Site Map | Index	Legal Disclaimer | Privacy Practices | Public Notices
©2008 Memorial Sloan-Kettering Cancer Center. 212-639-2000 1275 York Avenue New York, NY 10065.	PublicAffairs@mskcc.org