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Targeting of Proteins to Membranes by Fatty Acylation
Selected Publications
Liang X, Lu Y, Wilkes M, Neubert TA, Resh MD. Related Articles, Links
The N-terminal SH4 region of the Src family kinase Fyn is modified by methylation and heterogeneous fatty acylation: role in membrane targeting, cell adhesion, and spreading.
J Biol Chem. 2004 Feb 27;279(9):8133-9.
Resh MD. 1999 Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. Biochim Biophys Acta. 1999;1451:1-16.
van't Hof W, Resh MD. 1999 Dual fatty acylation of p59(Fyn) is required for association with the T cell receptor zeta chain through phosphotyrosine-Src homology domain-2 interactions. J Cell Biol. 1999;145:377-389.
Wolven A, Okamura H, Rosenblatt Y, Resh MD. 1997 Palmitoylation of p59fyn is reversible and sufficient for plasma membrane association. Mol Biol Cell. 1997;8:1159-1173.
van't Hof W, Resh MD. 1997 Rapid plasma membrane anchoring of newly synthesized p59fyn: selective requirement for NH2-terminal myristoylation and palmitoylation at cysteine-3. J Cell Biol. 1997 Mar 10;136(5):1023-35.
Liang X, Nazarian A, Erdjument-Bromage H, Bornmann W, Tempst P, Resh MD. 2001 Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction. J Biol Chem. 2001;276:30987-30994.
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Targeting of Proteins to Membranes by Fatty Acylation
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