Research Programs Cancer Biology & Genetics Cell Biology Computational Biology Developmental Biology Immunology Molecular Biology Molecular Pharmacology & Chemistry Structural Biology Jonathan Goldberg Christopher D. Lima Stephen B. Long Dimitar Nikolov Dinshaw J. Patel Nikola Pavletich Postdoctoral Training Graduate Education Summer Undergraduate Research Program Core Facilities Collaborative Research Centers Sloan-Kettering Institute > Research Programs > Structural Biology > Nikola Pavletich > Projects > The p53 Tumor Suppressor Selected Publications Cho Y, Gorina S, Jeffrey PD, Pavletich NP. (1994) Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science. 1994;265:346-355. Jeffrey PD, Gorina S, Pavletich NP. (1995) Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms. Science. 1995;267:1498-1502. Kussie PH, Gorina S, Marechal V, Elenbaas B, Moreau J, Levine AJ, Pavletich NP. (1996) Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science. 1996;274:948-953. Gorina S, Pavletich NP. (1996) Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2. Science. 1996;274:1001-1005. Huang L, Kinnucan E, Wang G, Beaudenon S, Howley PM, Huibregtse JM, Pavletich NP. (1999) Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade. Science. 1999;286:1321-1326. Return to The p53 Tumor Suppressor Main Page

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