Research Programs Cancer Biology & Genetics Cell Biology Computational Biology Developmental Biology Immunology Molecular Biology Molecular Pharmacology & Chemistry Structural Biology Jonathan Goldberg Christopher D. Lima Stephen B. Long Dimitar Nikolov Dinshaw J. Patel Nikola Pavletich Postdoctoral Training Graduate Education Summer Undergraduate Research Program Core Facilities Collaborative Research Centers Home > Sloan-Kettering Institute > Research Programs > Structural Biology > Nikola Pavletich > Projects > Cell Cycle Machinery Selected Publications Jeffrey PD, Russo AA, Polyak K, Gibbs E, Hurwitz J, Massague J, Pavletich NP. (1995) Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature. 1995;376:313-320. Russo AA, Jeffrey PD, Pavletich NP. (1996) Structural basis of cyclin-dependent kinase activation by phosphorylation. Nat Struct Biol. 1996;3:696-700. Russo AA, Jeffrey PD, Patten AK, Massague J, Pavletich NP. (1996) Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature. 1996;382:325-331. Russo AA, Tong L, Lee JO, Jeffrey PD, Pavletich NP. (1998) Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature. 1998;395:237-243. Lee JO, Russo AA, Pavletich NP. (1998) Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7. Nature. 1998;391:859-865. Zheng N, Fraenkel E, Pabo CO, Pavletich NP. (1999) Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes Dev. 1999;13:666-674. Return to Cell Cycle Machinery Main Page

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