Major Research Areas
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Cancer Biology & Genetics
Cell Biology
Computational Biology
Developmental Biology
Immunology
James Allison
Jayanta Chaudhuri
Lisa K. Denzin
Bo Dupont
Michael Glickman
Ulrich Hammerling
Alan Houghton
Morgan Huse
Ming Li
Richard O'Reilly
Lloyd Old
Eric Pamer
Derek Sant'Angelo
Marcel van den Brink
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Sloan-Kettering Institute
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Research Programs
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Immunology
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Lisa Denzin
Publications
Fallas JF, Tobin HM, Lou O, Guo D, Sant'Angelo DB, Denzin LK. Ectopic Expression of HLA-DO in mouse dendritic cells diminishes MHC class II antigen presentation. J Immunol. 2004;173:1549-1560.
Hake SB, Tobin HM, Steimle V, Denzin LK. Comparison of the transcriptional regulation of classical and non-classical MHC class II genes. Eur J Immunol. 2003;2361-2371.
Tolosa EW, Li Y, Yasuda W, Wienhold LK, Denzin A, Lautwein C, Driessen P, Schnorrer E, Weber S, Stevanovic R, Kurek A, Melms A, Brömme D. Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis. J Clin Invest. 2003;112:517-526.
Sant'Angelo DB, Robinson E, Janeway CA Jr, Denzin LK. Recognition of core and flanking amino acids of MHC class II-bound peptides by the T cell receptor. Eur J Immunol. 2002;32:2510-2520.
Glazier KS, Hake, SB, Tobin HM, Chadburn A, Schattner EJ, Denzin LK. Germinal center B cells regulate their capability to present antigen by modulation of HLA-DO. J Exp Med. 2002;195:1063-1069.
Sant'Angelo DB, Cresswell P, Janeway CA Jr, Denzin LK. Maintenance of TCR clonality in T cells expressing genes for two TCR heterodimers. Proc Natl Acad Sci USA. 2001;98:6824-6829.
Denzin LK, Sant'Angelo DB, Hammond C, Surman MJ, Cresswell P. Negative regulation by HLA-DO of MHC class II-restricted antigen processing. Science. 1997;278:106-109.
Denzin LK, Hammond C, Cresswell P. HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules. J Exp Med. 1996;184:2153-2166.
Denzin LK, Cresswell P. HLA-DM induces CLIP dissociation from MHC class II ab dimers and facilitates peptide loading. Cell 1995;82:155-165.
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