Major Research Areas

Publications

Hoyos B, Imam A, Chua R, Swenson C, Tong GX, Levi E, Noy N, Hammerling U. The cysteine-rich regions of the regulatory domains of Raf and protein kinase C as retinoid receptors. J Exp Med. 2000;192:835-846.

Imam A, Hoyos B, Swenson C, Levi E, Chua R, Viriya E, Hammerling U. Retinoids as ligands and coactivators of protein kinase C alpha. FASEB J. 2001;15:28-30.

Hoyos, B. , Imam, A., Korichneva, I., Levi, E., Chua, R., and Hammerling, U. Activation of c-Raf kinase by UV light:
Regulation by retinoids. J. Biol. Chem. 2002, 277:23949-23957

Korichneva, I., Hoyos, B., Chua, R., Levi, E., and Hammerling, U. Zinc-release from protein kinase C as the common event during activation by lipid second messenger or reactive oxygen. J. Biol. Chem. 2002, 277: 44327-44331.

Korichneva, I. Waka, J. and Hammerling U. Regulation of cardiac mitochondrial membrane potential by retinoids. J. Pharm. & Exp. Therapy. 2003 305:426-433

Hoyos, B. and Hammerling, U. Essential role of vitamin A in signal transduction. In: Carotenoids and Retinoids, Molecular Aspects and Health Issues. L. Packer, U.Obermuller-Jevic, K. Kraemer and H. Sies, Eds. AOCS Press, 2004 p 42-60.

Hoyos, B., Jiang, S. and Hammerling, U. Location and functional significance of retinol binding sites on the serine/threonine kinase, cRaf. J. Biol. Chem. 2005, 6872- 6878

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