Publications

Busam KJ, Iversen K, Berwick M, Spagnoli GC, Old LJ, Jungbluth AA. Immunoreactivity with the anti-MAGE antibody 57B in malignant melanoma: frequency of expression and correlation with prognostic parameters. Mod Pathol. 2000;13:459-465.

Güre AO, Stockert E, Arden KC, Boyer AD, Viars CS, Scanlan MJ, Old LJ, Chen Y-T. CT10: A new cancer-testis (CT) antigen homologous to CT7 and the MAGE family, identified by representational-difference analysis. Int J Cancer. 2000;85:726-732.

Güre AO, Stockert E, Scanlan MJ, Keresztes RS, Jäger D, Altorki NK, Old LJ, Chen Y-T. Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancer. Proc Natl Acad Sci USA. 2000;97:4198-4203.

Jäger E, Jäger D, Karbach J, Chen Y-T, Ritter G, Nagata Y, Gnjatic S, Stockert E, Arand M, Old LJ, Knuth A. Identification of NY-ESO-1 epitopes presented by HLA-DRB4 0101-0103 and recognized by CD4+ T lymphocytes of patients with NY-ESO-1 expressing melanoma. J Exp Med. 2000;191:625-630.

Jäger E, Nagata Y, Gnjatic S, Wada H, Stockert E, Karbach J, Dunbar PR, Lee SY, Jungbluth A, Jager D, Arand M, Ritter G, Cerundolo V, Dupont B, Chen Y-T, Old LJ, Knuth A. Monitoring CD8 T cell responses to NY-ESO-1: correlation of humoral and cellular immune responses. Proc Natl Acad Sci USA. 2000;97:4760-4765.

Jungbluth AA, Busam KJ, Kolb D, Iversen K, Coplan K, Chen Y-T, Spagnoli GC, Old LJ. Expression of MAGE-antigens in normal tissues and cancer. Int J Cancer. 2000;85:460-465.

Jungbluth AA, Iversen K, Coplan K, Kolb D, Stockert E, Chen Y-T, Old LJ, Busam K. T311 - an anti-tyrosinase monoclonal antibody for the detection of melanocytic lesions in paraffin-embedded tissues. Pathol Res Pract. 2000;196:235-242.

Rader C, Ritter G, Nathan S, Elia M, Gout I, Jungbluth AA, Cohen LS, Welt S, Old LJ, Barbas CF 3rd. The rabbit antibody repertoire as a novel source for the generation of therapeutic human antibodies. J Biol Chem. 2000;275:13668-13676.

Scanlan MJ, Altorki NK, Gure AO, Williamson B, Jungbluth A, Chen Y-T, Old LJ. Expression of cancer-testis antigens in lung cancer: definition of bromodomain testis-specific gene (BRDT) as a new CT gene, CT9. Cancer Lett. 2000;150:155-164.

Scanlan MJ, Gordan JD, Williamson B, Stockert E, Bander NH, Jongeneel V, Gure AO, Jäger D, Jäger E, Knuth A, Chen Y-T, Old LJ. Antigens recognized by autologous antibody in patients with renal-cell carcinoma. Int J Cancer. 1999;83:456-464.

Scanlan MJ, Williamson B, Jungbluth A, Stockert E, Arden KC, Viars CS, Gure AO, Gordan JD, Chen Y-T, Old, LJ. Isoforms of the human PDZ-73 protein exhibit differential tissue expression. Biochim Biophys Acta. 1999;1445:39-52.

Jungbluth AA, Iversen K, Coplan K, Williamson B, Chen Y-T, Stockert E, Old LJ, Busam KJ. Expression of melanocyte-associated markers gp-100 and Melan-A/MART-1 in angiomyolipomas. An immunohistochemical and rt-PCR analysis. Virchows Arch. 1999;434:429-435.

Jäger E, Stockert E, Zidianakis Z, Chen Y-T, Karbach J, Jäger D, Arand M, Ritter G, Old LJ, Knuth A. Humoral immune responses of cancer patients against "cancer testis" antigen NY-ESO-1: correlation with clinical events. Int J Cancer. 1999;84:506-510.

Dullenkopf W, Ritter G, Fortunato SR, Old LJ, Schmidt RR. Synthesis of a structurally defined antigen-immunostimulant combination for use in cancer vaccines. Chem Eur J. 1999;5:2432-2438.

Jäger D, Stockert E, Scanlan MJ, Güre AO, Jäger E, Knuth A, Old LJ, Chen Y-T. Cancer-testis antigens and ING1 tumor suppressor gene product are breast cancer antigens: characterization of tissue-specific ING1 transcripts and a homologue gene. Cancer Res. 1999;59:6197-6204.

Doi TS, Marino MW, Takahashi T, Yoshida T, Sakakura T, Old LJ, Obata Y. Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality. Proc Natl Acad Sci USA. 1999;96:2994-2999.

Trasler J, Saberi F, Somani IH, Adamali HI, Huang J-Q, Fortunato S.R., Ritter G, Gu M, Aebersold R, Gravel RA, Herno L. Characterization of the testis and epididymis in mouse models of human Tay Sachs and Sandhoff diseases and partial characterization of accumulated gangliosides. Endocrinology. 1998;139:3280-3288.

Jäger E, Chen Y-T, Drijfhout JW, Karbach J, Ringhoffer M, Jäger D, Arand M, Wada H, Noguchi Y, Stockert E, Old LJ, Knuth A. Simultaneous humoral and cellular immune response against "cancer-testis" antigen NY-ESO-1: Definition of HLA-A2 binding peptides epitopes. J Exp Med. 1998;265:265-270.

Busam KJ, Chen Y-T, Old LJ, Stockert E, Iversen K, Coplan KA, Rosai J, Barnhill L, Jungbluth AA. Expression of melan-A (MART-1) in benign melanocytic nevi and malignant melanoma. Am J Surg Pathol. 1998;22:976-982.

Catimel B, Scott AM, Lee FT, Hanai N, Ritter G, Welt S, Old LJ, Burgess AW, Nice EC. Direct immobilization of gangliosides onto gold-carboxymethyldextran sensor surfaces by hydrophobic interaction; applications to antibody characterization. Glycobiology. 1998;8:927-938.

Chen Y-T, Boyer AD, Viars CS, Tsang S, Old LJ, Arden KC. Genomic cloning and localization of CTAG, a gene endocing an autoimmunogenic cancer-testis antigen NY-ESO-1, to human chromosome Xq28. Cytogenetics Cell Genet. 1997;79:237-240.

Chen Y-T, Güre AO, Tsang S, Stockert E, Jäger E, Knuth A, Old LJ. Identification of multiple cancer/testis antigens by allogeneic antibody screening of a melanoma cell line library. Proc Natl Acad Sci USA. 1998;95:6919-6923.

Gure AO, Altorki NK, Stockert E, Scanlan MJ, Old LJ, Chen Y-T. Human lung cancer antigens recognized by autologous antibodies: definition of a novel cDNA derived from the tumor suppressor gene locus on chromosome 3p21.3. Cancer Res. 1998;58:1034-1041.

Kaplan DH, Shankaran V, Dighe AS, Stockert E, Aguet M, Old LJ, Schreiber RD. Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci USA. 1998;95:7556-7561.

Jungbluth AA, Busam KJ, Gerald WL, Stockert E, Coplan KA, Iversen K, McGregor DP, Old LJ, Chen Y-T. A103: an anti-melan-a monoclonal antibody for the detection of malignant melanoma in paraffin-embedded tissues. Am J Surg Pathol. 1998;22:595-602.

Liu J, Marino MW, Wong G, Grail D, Dunn A, Bettadapura J, Slavin AJ, Old LJ, Bernard CC. TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination. Nat Med. 1998;4:78-83.

Loh A, Sgouros G, O'Donoghue JA, Deland D, Puri D, Capitelli P, Humm JL, Larson SM, Old LJ, Divgi CR. Pharmacokinetic model of iodine-131-G250 antibody in patients with renal cell carcinoma. J Nucl Med. 1998;39:484-489.

Moritz RL, Ritter G, Catimel B, Cohen LS, Welt S, Old LJ, Burgess AW, Nice EC, Simpson RJ. Micro-sequencing strategies for the human A33 antigen, a novel surface glycoprotein of human gastrointestinal epithelium. J Chromatogr A. 1998;798:91-101.

Sahin U, Türeci Ö, Chen Y-T, Seitz G, Villena-Heinsen C, Old LJ, Pfreundschuh M. Expression of multiple cancer/testis (CT) antigens in breast cancer and melanoma: Basis for polyvalent CT vaccine strategies. Int J Cancer. 1998;78:387-389.

Scanlan MJ, Chen Y-T, Williamson B, Gure AO, Stockert E, Gordan JD, Türeci Ö, Sahin U, Pfreundschuh M, Old LJ. Characterization of human colon cancer antigens recognized by autologous antibodies. Int J Cancer. 1998;76:652-658.

Barendswaard EC, Scott AM, Divgi CR, Williams C Jr, Coplan K, Riedel E, Yao T-J, Gansow OA, Finn RD, Larson SM, Old LJ, Welt S. Rapid and specific targeting of monoclonal antibody A33 to a colon cancer xenograft in nude mice. Int J Oncol. 1998;12:45-53.

Türeci Ö, Chen Y-T, Sahin U, Gure AO, Zwick C, Villena C, Tsang S, Seitz G, Old LJ and Pfreundschuh M. Expression of SSX genes in human tumors. Int J Cancer. 1998;77:19-23.

Stockert E, Jäger E, Chen Y-T, Scanlan MJ, Gout I, Karbach J, Arand M, Knuth A, Old LJ. A survey of the humoral immune response of cancer patients to a panel of human tumor antigens. J Exp Med. 1998;187:1349-1354.

Busam KJ, Iversen K, Coplan KA, Old LJ, Stockert E, Chen Y-T, McGregor D, Jungbluth A. Immunoreactivity for A103, an antibody to melan-A (Mart-1), in adrenocortical and other steroid tumors. Am J Surg Pathol. 1998;22:57-63.

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