Publications

von Bubnoff N, Veach DR, Miller WT, Li W, Sänger J, Peschel C, Bornmann WG, Clarkson B, Duyster J. Inhibition of wild-type and mutant Bcr-Abl by pyrido‑pyrimidine-type small molecule kinase inhibitors. Cancer Res. 2003;63:6395-6404.

Strife A, Wisniewski D, Liu C, Lambek CL, Darzynkiewicz Z, Silver RT, and Clarkson B. Direct evidence that Bcr-Abl tyrosine kinase activity disrupts normal synergistic interactions between kit ligand and cytokines in primary primitive progenitor cells. Mol Cancer Res. 2003;1:176-185.

Netzer WJ, Dou F, Cai D, Veach D, Jean S, Li Y, Bornmann WG, Clarkson B, Xu H, Greengard P. Gleevec inhibits beta-amyloid production but not Notch cleavage. Proc Natl Acad Sci USA. 2003;100:12444-12449.

Nagar B, Hantschel O, Young MA, Scheffzek K, Veach D, Bornmann W, Clarkson B, Superti-Furga G, Kuriyan J. Structural basis for the autoinhibition of c-Abl tyrosine kinase. Cell. 2003;112:859-871.

Clarkson B, Strife A, Wisniewski D, Lambek CL, Liu C. Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies. Leukemia. 2003;17:1211-1262.

Wisniewski D, Lambek C, Liu C, Strife A, Veach D, Nagar B, Young MA, Schindler T, Bornmann W, Bertino JR, Kuriyan J, Clarkson B. Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases. Cancer Res. 2002;62:4244-4255.

Nagar B, Bornmann W, Pellicena P, Schindler T, Veach D, Miller TW, Clarkson B, Kuriyan J. Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571). Cancer Res. 2002;62:4236-4243.

Liang X, Wisniewski D, Strife A, Shivakrupa, Clarkson B and Resh MD. Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-kit signaling. J Biol Chem. 277:13732-13738, 2002.

Clarkson B. Chronic myelogenous leukemia: Prognosis and current status of treatment. In: Joseph R. Bertino, ed. Encyclopedia of Cancer, 2nd edition. California: Academic Press; 2002:519-524.

Clarkson B. Chronic myelogenous leukemia: Etiology, incidence, and clinical features. In: Joseph R. Bertino, ed. Encyclopedia of Cancer, 2nd edition. California: Academic Press; 2002:505-518.

Site Map \| Index	Legal Disclaimer \| Privacy Practices \| Public Notices

©2008 Memorial Sloan-Kettering Cancer Center. 212-639-2000 1275 York Avenue New York, NY 10065.	PublicAffairs@mskcc.org