Reviews:
* S.J. Danishefsky and M.T. Bilodeau, "Glycals in Organic Synthesis: The Evolution of New Strategies for the Convergent Assembly of Oligosaccharides and Other Glycoconjugates." Angew. Chem. Int. Ed., 35, 1380-1419 (1996).
* S.J. Danishefsky and J.R. Allen. "From the Laboratory to the Clinic: A Retrospective on Fully Synthetic Carbohydrate-Based Anti-Cancer Vaccines." Angewandte Chemie, 39, 836-863 (2000).
* O. Ouerfelli, J.D. Warren, R. Wilson, S.J. Danishefsky. "Synthetic Carbohydrate-Based Antitumor Vaccines: Challenges and Opportunities." Expert Review of Vaccines. 4(5), 677-685 (2005).
Clinical Trials:
* G. Ragupathi, S. Slovin, S. Adluri, D. Sames, I.-J. Kim, H. M. Kim, M. Spassova, W. G. Bornmann, K. O. Lloyd, H. I. Scher, P. O. Livingston and S. J. Danishefsky. "A Fully Synthetic Globo H Carbohydrate Vaccine Induces a Focused
Humoral Response in Prostate Cancer Patients: A Proof of Principle" Angew. Chem. Int. Ed. 38, 563-566 (1999).
* S. F. Slovin, G. Ragupathi, S Adluri, G. Ungers, K. Terry, S. Kim, M. Spassova, W. G. Bornmann, M. Fazzari, L. Danits, K. Olkiwicz, K. O. Lloyd, P.O. Livingston, S. J. Danishefsky, and H. I. Scher. "Carbohydrate Vaccines in Cancer: Immunogenicity of a Fully Synthetic Globo H Hexasaccharide Conjugate in Man." Proc. Nat. Acad. Sci. USA, 96, 5710-5715 (1999).
* Z.-G. Wang, L.J. Williams, X.-F. Zhang, A. Zatorski, V. Kudryashov, G. Ragupathi, M. Spassova, W. Bornmann, S.F. Slovin, H.I. Scher, P.O. Livingston, K.O. Lloyd, S.J. Danishefsky "Polyclonal Antibodies from Patients Immunized with a Globo H-KLH Vaccine: Isolation, Quantification, and Characterization of Immune Response Using Totally Synthetic Immobilized Tumor Antigens" Proc. Nat. Acad. Sci. 97, 2719-2724, (2000).
* P. Sabbatini, V. Kudryashov, S. Danishefsky, P.O. Livingston, G. Ragupathi, W. Bornmann, M. Spassova, A. Zatorski, D. Spriggs, C. Aghajanian, S. Soignet, M. Peyton, C. O'Flaherty, J. Curtin and K.O. Lloyd. "Immuniztion of Ovarian Cancer Patients with a Synthetic Lewisy-protein Conjugate Vaccine: Clinical and Serological Results." Int. J. Cancer, 87(1), 79-85, (2000).
* T. Gilewski, G. Ragupathi, S. Bhuta, L. J. Williams, C. Musselli, X.-F. Zhang, K. P. Bencsath, K. S. Panageas, J. Chin, L. Norton, A. N. Houghton, P. O. Livingston, S. J. Danishefsky "Immunization of Metastatic Breast Cancer Patients with a Fully Synthetic Carbohydrate Based Vaccine: A Phase I Trial" Proc. Nat. Acad. Sci. USA 98 (6), 3270-3275, (2001).
* S. F. Slovin, G. Ragupathi, C. Musselli, K. Olkiewicz, D. Verbel, S. D. Kuduk, J. B. Schwarz, D. Sames, S. Danishefsky, P. O. Livingston, H. I. Scher "Fully Synthetic Carbohydrate-Based Vaccines in Biochemically Relapsed
Prostate Cancer: Clinical Trial Results With ?-N-Acetylgalactosamine-O-Serine/Threonine Conjugate Vaccine" J. Clin. Oncology 21 (23) 4292-4298 (2003).
* L. M. Krug, G. Ragupathi, C. Hood, M. G. Kris, V. A. Miller, J. R. Allen, S. J. Keding, S. J. Danishefsky, J. Gomez, L. Tyson, B. Pizzo, V. Baez, P. O. Livingston. "Vaccination of Patients with Small-Cell Lung Cancer with Synthetic Fucosyl GM-1 Conjugated to Keyhole Limpet Hemocyanin." Clinical Cancer Research 10, 6094-6100 (2004).
* S. Slovin, G. Ragupathi, C. Musselli, C. Fernandez, M. Diani, D. Verbel, S. Danishefsky, P. Livingston, H. Scher. "Thomsen- Friedenreich (TF) Antigen as a Target for Prostate Cancer Vaccine: Clinical Trial Results with TF Cluster (c)-
KLH plus QS21 Conjugate Vaccine in Patients with Biochemically Relapsed Prostate Cancer." Clinical Cancer Immunology. 54, 694-702 (2005).
Multiantigenic Vaccines:
* S. J. Keding, S. J. Danishefsky "Prospects for total synthesis: A vision for a totally synthetic vaccine targeting epithelial tumors." Proc. Natl. Acad. Sci. USA 101 (33), 11937-11942 (2004).
* G. Ragupathi, F. Koide, P. O. Livingston, Y. S. Cho, A. Endo, Q. Wan, M. K. Spassova, S. J. Keding, J. Allen, S. J. Danishefsky "Preparation and Evaluation of Unimolecular Pentavalent and Hexavalent Antigenic Constructs Targeting Prostate and Breast Cancer: A Totally Synthetic Route to Anticancer Vaccines" J. Am. Chem. Soc. ASAP (2006).
