Research Programs Cancer Biology & Genetics Cell Biology Computational Biology Developmental Biology Immunology Molecular Biology David Allis @ Rockefeller.edu Jerard Hurwitz Prasad Jallepalli Scott Keeney Thomas J. Kelly Andrew Koff Kenneth J. Marians John Petrini Mark Ptashne Stewart Shuman Paul Tempst Iestyn Whitehouse Xiaolan Zhao Joint Appointees Simon N. Powell Molecular Pharmacology & Chemistry Structural Biology Postdoctoral Training Graduate Education Summer Undergraduate Research Program Core Facilities Collaborative Research Centers Home > Sloan-Kettering Institute > Research Programs > Molecular Biology > Prasad Jallepalli Publications Selected References P.V. Jallepalli and D. Pellman. Aneuploidy in the balance. Science. 2007; 317: 904-905. C. L. Randall, M.E. Burkard, and P.V. Jallepalli. Polo kinase and cytokinesis: harnessing the awesome power of chemical genetics. Cell Cycle. 2007; 6: 1713-1717. M.E. Burkard, C.L. Randall, S. Larochelle, C. Zhang, K.M. Shokat, R.P. Fisher, and P.V. Jallepalli. Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells. Proc Natl Acad Sci USA. 2007; 104: 4383-4388. S. Larochelle, K.A. Merrick, M.-E. Terret, L. Wohlbold, N.M. Barboza, C. Zhang, K.M. Shokat, P.V. Jallepalli, and R.P. Fisher. Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells. Molecular Cell. 2007; 25: 839-850. M.-E. Terret and P.V. Jallepalli. Meiosis: separase strikes twice. Nature Cell Biology. 2005; 8: 910-911. M. Papi, E. Berdougo, C.L. Randall, S. Ganguly, and P.V. Jallepalli. Multiple roles for separase auto-cleavage during the G2/M transition. Nature Cell Biology. 2005; 7: 1029-1035. S. Spinette, C. Lengauer, J.A. Mahoney, P.V. Jallepalli, Z. Wang, L. Casciola-Rosen, and A. Rosen. Ufd2, a novel autoantigen in scleroderma, regulates sister chromatid separation. Cell Cycle. 2004; 3: 1638-1644. Z. Wang, J.M. Cummins, D. Shen, D.P. Cahill, P.V. Jallepalli, T.L. Wang, D.W. Parsons, G. Traverso, M. Awad, N. Silliman, J. Ptak, S. Szabo, J.K. Willson, S.D. Markowitz, M.L. Goldberg, R. Karess, K. W. Kinzler, B. Vogelstein, V.E. Velculescu, and C. Lengauer. Three classes of genes mutated in colorectal cancers with chromosomal instability. Cancer Res. 2004; 64: 2998-3001. H. Rajagopalan, P.V. Jallepalli, V.E. Velculescu, K.W. Kinzler, B. Vogelstein, and C. Lengauer. Inactivation of hCDC4 can cause chromosomal instability. Nature. 2004; 428: 77-81. Jallepalli PV, Lengauer C, Vogelstein B, Bunz F. The Chk2 tumor suppressor is not required for p53 responses in human cancer cells. J Biol Chem. 2003; 278: 20475-20479. Nowak MA, Komarova NL, Sengupta A, Jallepalli PV, Shih IeM, Vogelstein B, Lengauer C. The role of chromosomal instability in tumor initiation. Proc Natl Acad Sci USA. 2002; 99: 16226-16231. Jallepalli PV, Lengauer C. Chromosome segregation and cancer: cutting through the mystery. Nat Rev Cancer. 2001; 1: 109-117. Jallepalli PV, Waizenegger IC, Bunz F, Langer S, Speicher MR, Peters JM, Kinzler KW, Vogelstein B, Lengauer C. Securin is required for chromosomal stability in human cells. Cell. 2001; 105: 445-457.

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