Research Programs Cancer Biology & Genetics Cell Biology Computational Biology Developmental Biology Immunology Molecular Biology Molecular Pharmacology & Chemistry Colin Begg Ronald Blasberg Luca Cartegni Gabriela Chiosis Bayard Clarkson Samuel Danishefsky Zvi Fuks David Y. Gin Hedvig Hricak Richard Kolesnick Steven Larson Yueming Li C. Clifton Ling Stephen Nimer Gavril Pasternak Jerome Posner Neal Rosen Michel Sadelain Peter Scardino David Scheinberg Francis M. Sirotnak Derek S. Tan Joint Appointees Jason Koutcher Jason Lewis Structural Biology Postdoctoral Training Graduate Education Summer Undergraduate Research Program Core Facilities Collaborative Research Centers Sloan-Kettering Institute > Research Programs > Molecular Pharmacology & Chemistry > Richard Kolesnick > Projects > Role of Membrane Rafts in the Response to Cytokines and Stress Selected Publications Cremesti A, Paris F, Grassme H, Holler N, Tschopp J, Fuks Z, Gulbins E, Kolesnick R. Ceramide enables Fas to cap and kill. J Biol Chem. 2001;276:23954-23961. Paris F, Grassme H, Cremesti A, Zager J, Fong Y, Haimovitz-Friedman A, Fuks Z, Gulbins E, Kolesnick R. Natural ceramide reverses Fas resistance of acid sphingomyelinase(-/-) hepatocytes. J Biol Chem. 2001;276:8297-8305. Grassme H, Jekle A, Riehle A, Schwarz H, Berger J, Sandhoff K, Kolesnick R, Gulbins E. CD95 signaling via ceramide-rich membrane rafts. J Biol Chem. 2001;276:20589-20596. Kolesnick R. The therapeutic potential of modulating the ceramide/sphingomyelin pathway. J Clin Invest. 2002;110:3-8.

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