Our Clinical Trials for Brain Tumors


	Promising Brain Tumor Clinical Trials Presented by Antonio Omuro, MD, Neuro-Oncologist

Here you can find a continually updated listing of Memorial Sloan-Kettering's current clinical trials for cancers of the brain and spinal cord. Trials are listed according to the type of tumor. To learn more about a study, choose from the list below.

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Gliomas
Primary Central Nervous System (CNS) Lymphoma
Brain Metastases
Other Trials
Pediatric Brain Tumors

Gliomas

A Phase I Study of XL765 in Combination with Temozolomide in Patients with Malignant Gliomas
Omuro, Antonio, MD

[Protocol 08-057]
A Phase II Study of Bevacizumab, Temozolomide and Hypofractionated Radiotherapy for Patients with Newly Diagnosed Glioblastoma
Omuro, Antonio, MD

[Protocol 08-126]
A Phase II Study of TLN-4601 in Patients with Glioblastoma Multiforme
Omuro, Antonio, MD

[Protocol 08-160]
A Phase II Trial of Continuous Low-Dose Temozolomide for Patients with Recurrent Malignant Glioma
Omuro, Antonio, MD

[Protocol 07-064]
A Phase II Trial of Dasatinib in Patients with Recurrent Glioblastoma Multiforme
Lassman, Andrew, MD

[Protocol 07-042]
A Phase II Trial of Intensive Chemotherapy & Autotransplantation in Patients with Newly Diagnosed Anaplastic Oligodendroglioma
Omuro, Antonio, MD

[Protocol 02-089]
A Phase II Trial of Temozolomide and Radiotherapy Followed by Temozolomide and Maintenance Cis-retinoic Acid for Patients with Newly Diagnosed Gliomas
Lassman, Andrew, MD

[Protocol 05-079]
Image-Guided Stereotactic Biopsy of High Grade Gliomas
Bradbury, Michelle, MD

[Protocol 09-060]
Phase I Study of Aflibercept With or After Radiation Therapy and Temozolomide in Patients with Malignant Glioma
Omuro, Antonio, MD

[Protocol 08-106]
Phase I/II Study of BAY 43-9006 (Sorafenib) in Combination with Several Other Drugs in Patients with Gliomas
Omuro, Antonio, MD

[Protocol 06-109]
Phase I/II Study of Vandetanib with Radiation Therapy and Concomitant and Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma
Lassman, Andrew, MD

[Protocol 08-137]
[¹⁸F]FACBC PET imaging for gliomas
Lassman, Andrew, MD

[Protocol 08-142]

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Primary Central Nervous System (CNS) Lymphoma

A Phase II Study of Rituximab, Methotrexate, Procarbazine and Vincristine Followed by High-Dose Chemotherapy with Autologous Stem Cell Rescue in Newly Diagnosed Primary CNS Lymphoma
Omuro, Antonio, MD

[Protocol 04-129]

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Brain Metastases

A Phase II Study of Intrathecal I¹³¹-3F8 in Patients with GD2-Expressing Central Nervous System and Leptomeningeal Neoplasms
Kramer, Kim, MD

[Protocol 05-122]
A Phase II Trial of Patupilone in Patients with Brain Metastases from Breast Cancer
Seidman, Andrew, MD

[Protocol 07-036]
A Study of [¹⁸F]-ML-10 as a PET Imaging Radiotracer for the Early Detection of Response of Brain Metastases of Solid Tumors to Radiation Therapy
Beal, Kathryn, MD

[Protocol 08-116]

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Other Trials

A Phase II Trial of Sunitinib (Sutent^®) in Patients with Recurrent or Inoperable Meningioma
Kaley, Thomas, MD

[Protocol 07-135]
Adjunctive Donepezil Therapy and Genetic Risk Factors of Cognitive Dysfunction in Brain Tumor Survivors
Correa, Denise, PhD

[Protocol 04-122]
GLIOGENE: Genetic Epidemiology of Glioma International Consortium
Bernstein, Jonine, PhD

[Protocol 07-137]
Structural Imaging and Cognitive Functions in Adult Stem Cell Transplant Recipients Treated with Radiation Therapy and Chemotherapy
Correa, Denise, PhD

[Protocol 06-162]

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Pediatric Brain Tumors

A Phase I Study of Intrathecal Radioimmunotherapy Using ¹³¹I-8H9 for Central Nervous System/Leptomeningeal Cancers
Kramer, Kim, MD

[Protocol 03-133]
A Phase II Study of Conformal Radiotherapy in Patients with Low-Grade Gliomas
Dunkel, Ira, MD

[Protocol 07-049]
A Phase II Study of Intrathecal I¹³¹-3F8 in Patients with GD2-Expressing Central Nervous System and Leptomeningeal Neoplasms
Kramer, Kim, MD

[Protocol 05-122]
A Phase III Study Assessing Carboplatin and/or Isotretinoin plus Radiation in Patients with Supratentorial Primitive Neuroectodermal Tumor or High-Risk Medulloblastoma
Gilheeney, Stephen, MD

[Protocol 07-174]
A Phase III Study of Intensive Induction Chemotherapy with or without Methotrexate Followed by Consolidation Therapy with Stem Cell Rescue in Young Children Newly Diagnosed with Supratentorial PNET or High-Risk Medulloblastoma
Gilheeney, Stephen, MD

[Protocol 07-170]
Phase I Study of Single Agent Perifosine for Recurrent Pediatric Solid Tumors
Becher, Oren, MD

[Protocol 08-091]
Phase II Study of Nimotuzumab (TheraCIM^®) in Pediatric Patients with Recurrent Diffuse Intrinsic Pontine Glioma
Trippett, Tanya, MD

[Protocol 08-034]
Radiotherapy Alone versus Chemotherapy Followed by Response-Based Radiotherapy for Newly Diagnosed Primary CNS Germinoma
Dunkel, Ira, MD

[Protocol 07-167]
Treatment of Atypical Teratoid/Rhabdoid Tumors of the Central Nervous System with Surgery, Intensive Chemotherapy, and 3-D Conformal Radiation
Dunkel, Ira, MD

[Protocol 09-070]

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