Postdoctoral Fellow with
Prof. Benjamin F. Cravatt, III
Department of Chemical Physiology
The Skaggs Institute for Chemical Biology
The Scripps Research Institute
PhD, Weill Cornell Medical College, 2009
Tri-Institutional Training Program in Chemical Biology
BS, University of California, Berkeley, 2003
Thesis: Design and Synthesis of Inhibitors of Nonribosomal Peptide Synthetase Adenylation Domains, May 13, 2009
Publications
1 Patent Application
3)
Cisar, J. S.; Tan, D. S.* "Small molecule inhibition of microbial natural product biosynthesis – An emerging antibiotic strategy." Chem. Soc. Rev.2008, 37, 1320–1329.
[ Abstract | PDF | PMC ]
2)
Cisar, J. S.; Ferreras, J. A.; Soni, R. K.; Quadri, L. E. N.*; Tan, D. S.* "Exploiting ligand conformation in selective inhibition of non-ribosomal peptide synthetase amino acid adenylation with designed macrocyclic small molecules." J. Am. Chem. Soc.2007, 129, 7752–7753.
[ Abstract | PDF | Supporting Info | PMC ]
Song, J.; Cisar, J. S.; Bertozzi, C. R.* "Functional self-assembling bolaamphiphilic polydiacetylenes as colorimetric sensor scaffolds." J. Am. Chem. Soc.2004, 126, 8459–8465.
[ Abstract | PDF ]
News Articles
08/18/2008
From Peptides to Polymers: Molecular probes for biological investigation (NYAS eBriefing)
Chemical biologists seek to design new chemical tools for use in research and medicine. Their search is predicated on the incredible diversity of chemical structures, both natural and otherwise. This diversity was well represented at the Chemical Biology Discussion Group's Special Year-End Meeting, held June 2, 2008.
[Overview (free) | Meeting report (membership req'd)]
Justin Cisar's seminar: Inhibition of Nonribosomal Peptide Synthetase Amino Acid Adenylation Domains
[Video (membership req'd)]