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Improving Functional Outcomes in Patients with Unilateral Vocal Cord Paralysis: Assessment of Adaptation Using Functional Magnetic Resonance Imaging
[Protocol 05-036]
- Full Title :
- IMPROVING FUNCTIONAL OUTCOMES IN PATIENTS WITH UNILATERAL VOCAL CORD PARALYSIS: ASSESSMENT OF ADAPTATION USING FUNCTIONAL MAGNETIC RESONANCE IMAGING
- Purpose :
Vocal cord paralysis is a potential complication of thoracic cancers, such as lung and esophageal cancers, and sometimes head and neck cancers. The purpose of this study is see how the brain "re-learns" to control the larynx (voicebox) during speaking and swallowing when undergoing surgical rehabilitation for unilateral (one-sided) vocal cord paralysis. Healthcare professionals need information on how the brain re-learns to control speaking and swallowing so they can improve the healing of patients who are being treated for unilateral vocal cord paralysis.
In this study, researchers will use functional magnetic resonance imaging (fMRI) to image patients' brains as they speak and swallow. They will produce "brain maps" that correspond to speaking, swallowing, and hand movements. The results of the fMRI scans will be compared between patients with unilateral vocal cord paralysis and healthy subjects.
- Eligibility :
To be eligible for this study, patients must meet several criteria, including but not limited to the following:
- Patients must have unilateral vocal cord paralysis and be undergoing type I thyroplasty as rehabilitation to improve their speech and swallowing.
- Healthy subjects must be ages 18 to 85.
- All participants must be able to undergo MRI.
For more information and to see if you are eligible for this study, please contact Dr. Dennis Kraus at 212-639-5621.
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