Many patients with primary liver cancer have no symptoms at all. In some instances, jaundice (when the skin and the whites of the eyes become yellow, urine darkens, and the color of stool becomes lighter than normal), malaise, or a general feeling of poor health, loss of appetite, weight loss, fever, fatigue, bloating, itching, swelling of the legs, or a sense of general weakness may be present. Abdominal pain or discomfort may also occur.