Dr. Engel's main research interests are in environmental and occupational risk factors for cancer and the role of genetic susceptibility. Dr. Engel is the Principal Investigator of a study examining the relationship of blood levels of organochlorines and aflatoxins with the risk of primary liver cancer. He is also Principal Investigator of a study of sun exposure and genetic variation in the vitamin D pathway in relation to the risk of breast cancer. In addition, he is conducting a study of the association between germline genetic polymorphisms and genetic mutations in tumors among patients with rare gastrointestinal stromal tumors. He continues to collaborate with colleagues at the National Cancer Institute, the Centers for Disease Control, and the Norwegian Cancer Registry on a study of serum organochlorine levels and risk of selected cancers.
Selected Bibliography:
Engel LS, Keifer MC, Zahm SH. Comparison of a traditional questionnaire with an icon/calendar-based questionnaire to assess occupational history. Am J Ind Med 2001; 40:502-511.
Engel LS, Vaughan TL, Gammon MD, Chow WH, Risch HA, Dubrow R, Mayne ST, Rotterdam H, Schoenberg JB, Stanford JL, West AB, Blot WJ, Fraumeni JF. Occupation and risk of esophageal and gastric cardia adenocarcinoma. Am J Ind Med 2002;42:11-22.
Engel LS, Taioli E, Pfeiffer R, Garcia-Closas M, Marcus PM, Lan Q, Boffetta P, Vineis P, Autrup H, Bell DA, Branch RA, Brockmoller J, Daly AK, Heckbert SR, Kalina I, Kang D, Katoh T, Lafuente A, Lin HJ, Romkes M, Taylor JA, Rothman N. Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: a HuGE review. Am J Epidemiol 2002; 156:95-109.
Engel LS, Chow WH, Vaughan TL, Gammon MD, Risch HA, Stanford JL, Schoenberg JB, Mayne ST, Dubrow R, Rotterdam H, West AB, Blaser M, Blot WJ, Gail MH, Fraumeni JF. Population attributable risks of esophageal and gastric cancers. J Natl Cancer Inst 2003;95:1404-1413.
Engel LS, Hill DA, Hoppin JA, Lubin JH, Lynch CF, Pierce J, Samanic C, Sandler DP, Blair A, Alavanja MC. Pesticide Use and Breast Cancer Risk among Farmers' Wives in the Agricultural Health Study. Am J Epidemiol 2005;161:121-35.
