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Publications

Veach DR, Namavari M, Beresten, Balatoni TJ, Minchenko M, Djaballah H, Finn RD, Clarkson B, Gelovani JG, Bornmann, WG and Larson SM (2005) "Synthesis and in vitro examination of [124I]-, [125I]- and [131I]-2-(4-iodophenylamino) pyrido[2,3-d]pyrimidin-7-one radiolabeled Abl kinase inhibitors" Nuclear Medicine and Biology 32:313-321.

Poster Presentation (SBS 2006) Development and Validation of a Sequential Strategy to Screen for Inhibitors of the Heterodimeric Kinase Cdc7:Dbf4. Shum D., Santos R., Radu C., Venkatraman E., Djballah H., Frattini M. Molecular Pharmacology & Chemistry Program, Molecular Biology Program, Department of Medicine, Memorial Sloan-Kettering Cancer Center, NY, 10065, USA

Poster Presentation (SBS 2006) Development and Validation of a Fluorescence Polarization Based Binding Assay for Human Peptide Deformylase. Antczak, C., Shum D., Escobar S., Venkatraman E., Bassit B., Yang G., Ouerfelli O., Li Y., Djaballah H., Scheinberg D. Molecular Pharmacology & Chemistry Program, Memorial Sloan-Kettering Cancer Center, NY, 10065, USA.

Poster Presentation (LabAutomation 2006) Assay Miniaturization into 1536 Well Microtiter Plates: The Memorial Sloan Kettering Cancer Center Experience. Radu C., Liu J., Kim E., Yiu F., Djaballah H. HTS Core Facility, Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, NY, USA. Apricot Designs Inc., Monrovia, CA, USA

Poster Presentation (American Association for Cancer Research 2006) Profiling of leukemic and lymphoma cell lines using small molecules: In search of conserved and novel chemical scaffold signatures effective for specific diseases. Frattini M., Shum D., Cromwell A., Santos R., Djaballah H., Kelly T. Department of Medicine, Molecular Biology Program, Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, NY, USA

Antczak, C, Shum, D, Escobar, S, Bassit, B, Kim, E, Venkatraman, E, Wu, N, Yang, G, Ouerfelli, O, Li, Y, Scheinberg, DA, Djaballah, H (2007) "High-throughput Identification of Inhibitors of the Cancer Target Human Mitochondrial Peptide Deformylase" J Biomol Screen 12:521-535.

Ramajayam R, Gididhar, R, Yadav, MR, Djaballah H, Shum, D, Radu, C (2007) "Synthesis and antiproliferative activity of some diaryldiazepines and diarylpyrimidines" J Enz Inhib Med Chem 22:716-721.

Poster presentation (SBS Meeting 2007) "A High-throughput Strategy for the Identification of the First Non-peptidomimetic Inhibitors Selective for Human Peptide Deformylase" Christophe Antczak, David Shum, Constantin Radu, Earl Kim, David A. Scheinberg, Hakim Djaballah. Molecular Pharmacology & Chemistry Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA

Poster presentation (SBS Meeting 2007) "Development and Validation of a Sequential Strategy to Screen for Inhibitors of the EphB2/ephrinA5 Complex" David Shum1, Juha P. Himanen 2, Constantin Radu1, Dimitar B. Nikolov2 and Hakim Djaballah1. 1Molecular Pharmacology & Chemistry Program, 2Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, 10065, USA

Poster presentation (SBS Meeting 2007) "Development of a High Content Assay to Study DNA Damage Response" David Shum1, Yi Gong2, Constantin Radu1,Gabriela E. Sanchez1, Venkatraman E. Seshan1, Titia de Lange2 and Hakim Djaballah1. 1Molecular Pharmacology & Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, 10065, USA, 2Laboratory for Cell Biology and Genetics, 2The Rockefeller University, New York, 10021, USA

Poster presentation (SBS Meeting 2007) "Development of a 1536-well Format Assay to Screen for Inhibitors of ã-Secretase" David Shum, Christopher C. Shelton, Constantin Radu, Yueming Li and Hakim Djaballah. Molecular Pharmacology & Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, 10065
, USA

Poster presentation (SBS Meeting 2007) "Development of a High-density Fluorescence Polarization-based Assay for Nucleotide-dependent Phosphatases Using the Transcreener™ Technology" Christophe Antczak, Anthony Ciro, Gabriela Sanchez and Hakim Djaballah. Molecular Pharmacology & Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, 10065, USA

Veach DR, Namavari M, Pillarsetty N, Santos EB, Beresten-Kochetkov T, Lambek C, Punzalan BJ, Antczak C, Smith-Jones PM, Djaballah H, Clarkson B, Larson SM (2007) "Synthesis and biological evaluation of a fluorine-18 derivative of dasatinib" J Med Chem 50:5853-5857.

Deng L, Dai P, Ciro A, Smee DF, Djaballah H, Shuman S (2007) "Identification of novel antipoxviral agents: Mitoxantrone inhibits vaccinia virus replication by blocking virion assembly" J Virology 81:13392-402.

Ramajayam R, Gididhar, R, Yadav, MR, Balaraman R, Djaballah H, Shum, D, Radu, C (2008) "Synthesis, antileukemic and antiplatelet activities of 2,3-diaryl-6,7-dihydro-5H-1,4-diazepines" Eur J Med Chem (in press)

Shum D, Radu C, Kim E, Cajuste M, Shao Y, Seshan V.E., Djaballah H (2008) "A high density assay format for the detection of novel cytotoxic agents in large chemical libraries" J Enz Inhib Med Chem (in press)

Eckelbarger JD, Wilmot JT, Epperson MT, Thakur CS, Shum D, Antczak C, Tarassishin L, Djaballah H, Gin DY (2008) "Synthesis of Antiproliferative Cephalotaxus Esters and Their Evaluation against Several Human Hematopoietic and Solid Tumor Cell Lines: Uncovering Differential Susceptibilities to Multi-Drug Resistance" Chem Eur J 14:1-15

Antczak C, Radu C, Djaballah H (2008) "A Profiling Platform for the Identification of Selective Metalloprotease Inhibitors" J Biomol Screen 13:285-294

Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L (2008) High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells Cell Stem Cell 2:602-12.

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