Research Programs Cancer Biology & Genetics Cell Biology Computational Biology Developmental Biology Kathryn Anderson Zhirong Bao Mary K. Baylies Peter Besmer Anna-Katerina Hadjantonakis Maria Jasin Alexandra Joyner Julia Kaltschmidt Elizabeth Lacy Eric Lai Songhai Shi Lorenz Studer Nicholas Tolwinski Jennifer Zallen Immunology Molecular Biology Molecular Pharmacology & Chemistry Structural Biology Postdoctoral Training Graduate Education Summer Undergraduate Research Program Core Facilities Collaborative Research Centers Sloan-Kettering Institute > Research Programs > Developmental Biology > Eric Lai > Projects > Notch Signaling Selected Publications Lai, E. C., F. Roegiers, X. Qin, Y. N. Jan and G. M. Rubin (2005). The ubiquitin ligase Drosophila Mind Bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development 132: 2319-2332. Lai, E. C. (2004). Notch signaling: control of cell communication and cell fate. Development 131: 965-973. Lai, E. C. (2002). Protein degradation: Four E3s for the Notch pathway. Current Biology 12: R74-78. Lai, E. C., G. A. Deblandre, C. Kintner and G. M. Rubin (2001). Drosophila Neuralized is a ubiquitin ligase that promotes internalization and degradation of Delta. Developmental Cell 1: 783-794. Lai, E. C. and G. M. Rubin (2001). Neuralized functions cell-autonomously to regulate a subset of Notch-dependent processes during adult Drosophila development. Developmental Biology 231: 217-233. Lai, E. C. and G. M. Rubin (2001). Neuralized is essential for a subset of Notch pathway-dependent cell fate decisions during Drosophila eye development. Proc. Natl. Acad. Sci. USA. 98: 5637-5642.

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