3. If I take strong pain medicines such as opioids early on, will I run out of options if my pain gets worse later?
Depending on need, opioids may be prescribed at any stage of treatment. There is no need to "tough it out" early in treatment out of concern that strong pain medicines won't be effective if needed later on. Some people, but not all, develop drug tolerance, which means their body has become accustomed to the medication. When a medication doesn't relieve pain as well as it did, the dose can be adjusted or another type of medication or treatment can be prescribed. Patients may receive increasing doses of opioids for years without becoming addicted, or psychologically dependent. When the need for pain relief subsides, physical dependence can usually be managed without withdrawal symptoms by tapering the opioid before discontinuing.