Major Research Areas

Publications

Frequent unanticipated alleles of lethal giant larvae in Drosophila second chromosome stocks.
Roegiers F, Kavaler J, Tolwinski N, Chou YT, Duan H, Bejarano F, Zitserman D, Lai EC.
Genetics. 2009 May;182(1):407-10. Epub 2009 Mar 11.

Wnt signaling pathways meet Rho GTPases. Schlessinger K, Hall A, Tolwinski N. Genes Dev. 2009 Feb 1;23(3):265-77. Review.

Membrane Bound Axin Is Sufficient for Wingless Signaling in Drosophila Embryos. Tolwinski NS. Genetics. 2009 Jan 5.

Reptin and Pontin function antagonistically with PcG and TrxG complexes to mediate Hox gene control. Diop SB, Bertaux K, Vasanthi D, Sarkeshik A, Goirand B, Aragnol D, Tolwinski NS, Cole MD, Pradel J, Yates JR 3rd, Mishra RK, Graba Y, Saurin AJ. EMBO Rep. 2008 Mar;9(3):260-6. Epub 2008 Feb 8.

An insect symbiosis is influenced by bacterium-specific polymorphisms in outer-membrane protein A. Weiss BL, Wu Y, Schwank JJ, Tolwinski NS, Aksoy S.
Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15088-93. Epub 2008 Sep 24.

Advances in pattern formation: Signaling and transcription. Tolwinski NS. Fly (Austin). 2008 May 26;2(3).

Rethinking WNT signaling. Nicholas Tolwinski and Eric Wieschaus. Trends in Genetics. 2004 Apr;20(4):177-81.

A nuclear function for armadillo/beta-catenin. Nicholas Tolwinski and Eric Wieschaus. PLoS Biology. 2004 Apr;2(4):E95. Epub 2004 Feb 10.

Wingless/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity. Nicholas Tolwinski, Marcel Wehrli, Anna Rives A, Naz Erdeniz, Stephen DiNardo, and Eric Wieschaus. Developmental Cell. 2003 Mar;4(3):407-18.

Armadillo nuclear import is regulated by cytoplasmic anchor Axin and nuclear anchor dTCF/Pan. Nicholas Tolwinski and Eric Wieschaus. Development. 2001 Jun;128(11):2107-17.

Wnt, Hedgehog and Junctional Armadillo/beta-Catenin Establish Planar Polarity in the Drosophila Embryo. Pamela Colosimo and Nicholas Tolwinski. PLoS ONE. 2006 Dec 20

Epithelial Polarity: Interactions between Junctions and Apical-Basal Machinery.
Kaplan NA, Liu X, Tolwinski NS.
Genetics. 2009 Sep 7

GSK3beta affects apical-basal polarity and cell-cell adhesion by regulating aPKC levels.
Colosimo PF, Liu X, Kaplan NA, Tolwinski NS.
Dev Dyn. 2009 May 6

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