History & Overview Annual Report President's Pages Center News Community Affairs
Make a Gift Yankees Universe Fund Fred's Team Thomas Blake Sr. Memorial Research Fund Donating Blood & Platelets Volunteering Thrift Shop Park Avenue Potluck Cookbook
Press Releases Information for Journalists News@MSKCC
Manhattan New Jersey Long Island Westchester
Working at Memorial Sloan-Kettering Work Sites College Recruitment About Nursing Job Fairs & Career Days Job Search & Apply Online
Making an Appointment
Newly Diagnosed?
We Can Help
Newly Diagnosed?<br>We Can Help
Getting the correct diagnosis and the most appropriate treatment from the start is crucial

This section includes descriptions of several rare blood cancers. These blood disorders develop when the normal process of blood cell growth and development (hematopoiesis) breaks down and a malignancy of the blood cells arises. Abnormally large quantities of a specific type of blood cell are produced in the bone marrow or lymphatic tissues, or abnormal blood cells are produced that do not function properly.

Among the uncommon blood cancers outlined are lymphoproliferative disorders (diseases of white blood cells called T cells and B cells); myeloproliferative disorders (diseases in which too many of certain types of blood cells are made in the bone marrow); and four other uncommon blood disorders -- eosinophilia, histiocytosis, paroxysmal nocturnal hemoglobinuria, and systemic mastocytosis.

Patients with any blood cancer that occurs relatively infrequently may have difficulty finding information about where and from whom to obtain the best treatment. All patients with cancer should seek care from a physician or team experienced in treating his or her disease, and this is especially important for patients with rare blood cancers, because these diseases may be difficult to diagnose -- but are sometimes easily treated if diagnosed correctly. Many Memorial Sloan-Kettering physicians have developed unequaled expertise in diagnosing and treating some of the rarest forms of cancer.

  • Our Approach & Expertise
    At Memorial Sloan-Kettering Cancer Center, state-of-the-art treatment for a variety of cancers that develop in the bone marrow, blood, or lymph nodes is carried out by experts on the Hematology Disease Management Team.
  • Uncommon Lymphoproliferative Disorders
    Lymphoproliferative disorders are those in which lymphocytes, white blood cells produced in the lymphatic tissue (the lymph nodes, spleen, thymus, for example), are over-produced or act abnormally.
  • Uncommon Myeloproliferative Disorders
    Myeloproliferative disorders are diseases in which too many of certain types of blood cells - monocytes, platelets, fibroblasts, red blood cells -- are made in the bone marrow, the spongy tissue inside the large bones in the body where red and white blood cells and platelets are made.
  • Eosinophilia
    Patients with eosinophilia have an abnormally high number of eosinophils, a type of white blood cell, in their blood.
  • Histiocytosis
    Histiocytosis, also called Langerhans' cell histiocytosis or eosinophilic granuloma, is a condition marked by the abnormal appearance of histiocytes (macrophages) in the tissues.
  • Paroxysmal Nocturnal Hemoglobinuria
    Paroxysmal nocturnal hemoglobinuria (PNH) results from a mutation in a hematopoietic stem cell; the mutated cell then expands in the bone marrow.
  • Systemic Mastocytosis
    In patients with systemic mastocytosis, the mast cells (cells involved in allergic reactions) are present in excess numbers.

PrintEmail This Page