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Squamous cell carcinoma is the second most common form of skin cancer, accounting for about 20 percent of skin cancers in the United States. The vast majority of squamous cell carcinomas can be cured when detected early. However, this type of skin cancer can be more difficult to treat and can cause cosmetic damage if not treated immediately.

In this section, you can find up-to-date information about squamous cell carcinoma and learn about Memorial Sloan-Kettering's expertise in treating patients with this common form of skin cancer.

  • Our Approach & Expertise
    Memorial Sloan-Kettering provides comprehensive, multidisciplinary care to patients with basal cell and squamous cell carcinoma (non-melanoma skin cancer) each year.
  • Overview
    Squamous cell carcinomas are most commonly found on areas of the body that are frequently exposed to the sun, including the ears, face, and mouth.
  • Risk Factors
    Exposure to ultraviolet (UV) radiation is the single most important cause of skin cancer, especially when the exposure resulted in sunburn and blistering. Overexposure to UV radiation (UVB radiation in particular) is the most common risk factor associated with squamous cell carcinoma.
  • Prevention & Early Detection
    The best way to prevent skin cancer is to protect yourself and your family from excessive exposure to sunlight -- and not only when you go to the beach.
  • Symptoms
    Squamous cell carcinomas may develop from a flat area showing only slight changes from normal skin. A new growth, a spot or bump that gets larger over months or years, or a sore that doesn't heal are warning signs.
  • Diagnosis
    Most suspected skin cancers are first noticed by the patient or by a family member and brought to the attention of a doctor.
  • Treatment
    Most squamous cell carcinomas can be cured with minor surgery. Treatment options may include curettage and electrodesiccation, radiation therapy, cryosurgery, and laser surgery.
  • Survivorship & Support
    Even after successful treatment, squamous cell carcinomas can recur in the same place. Also, people who have one skin cancer are at higher risk than average for skin cancers of all types. For these reasons, ongoing follow-up examinations by the cancer care team are essential.

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