Major Research Areas
Cell Biology
Engelhardt M, MacKenzie K, Drullinsky P, Silver RT, Moore MAS. Telomerase activity and telomere length in acute and chronic leukemia, pre- and post-ex vivo culture. Cancer Research 2000; 60: 610-617

Mackenzie KL, Hackett NR, Crystal RG, Moore MAS. . Adenoviral vector-mediated gene transfer to primitive human hematopoietic progenitor cells: Transduction and quantification in long-term culture.. Blood 2000; 96: 100-108

Mulloy JC, Cammenga J, MacKenzie KL, Moore MAS, Nimer SD. . The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells.. Blood 2002; 99: 15-23

Ghannam G, Takeda A, Camarata T, Moore MA, Viale A, Yaseen NR. The oncogene Nup98-HOXA9 induces gene transcription in myeloid cells. J Biol Chem. 2004, 279:866-75.

Zhang Y, Morrone G, Zhang J, Chen X, Lu X, Ma L, Moore M, Zhou P. CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein. EMBO J. 2003, 22:6057-6067.

Moore MAS. The "Stem Cell Leukemia" Gene: What's in a Name? Blood 2004. 103: 3249-50.

Nimer SD, Moore MAS. Effects of the leukemia-associated AML1/ETO protein on hematopoietic stem and progenitor cells. Oncogene. 2004, 23:4249-54.

Moldenhauer A, Frank RC, Pinilla-Ibarz J, Holland G, Boccuni P, Scheinberg D, Salama A, Seeger K, Moore MA, Nimer SD. Histone deacetylase inhibition improves dendritic cell differentiation of leukemic blasts with AML1-containing fusion proteins. J Leukoc Biol. 2004, 76:623-633.

Schuringa JJ, Chung KY, Morrone G, Moore MAS. Constitutive activation of STAT5 promotes human hematopoietic stem cell self-renewal and erythroid differentiation. J Exp Med. 2004, 2000:623-635.

Schuringa JJ, Wu K, Morrone G, Moore MA. Enforced activation of STAT5A facilitates the generation of embryonic stem-derived hematopoietic stem cells that contribute to hematopoiesis in vivo. Stem Cells. 2004, 22:1191-1204.

Chung KY, Morrone G, Schuringa JJ, Wong B, Dorn DC, Moore MA. Enforced expression of an Flt3 internal tandem duplication in human CD34+ cells confers properties of self-renewal and enhanced erythropoiesis. Blood. 2005, 105:77-84.

Mulloy JC, Cammenga J, Berguido FJ, Wu K, Zhou P, Comenzo RL, Jahnwar S, Moore MAS, Nimer SD. Maintaining the
self-renewal and differentiation potential of human CD34+ hematopoietic stem cells using a single genetic element.
Blood. 2003, 102:4369-76.

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