Major Research Areas
Cell Biology
Jo D-Y, Rafii S, Hamada T, Moore MAS. Chemotaxis of primitive hematopoietic cells in response to stromal cell-derived
factor-1. J. Clin Invest 2000; 105:101-111.

Lane WJ, Dias S, Hattori K, Heissig B, Choy M, Rabbany SY, Wood J, Moore MAS, Rafii S. Stromal-derived factor 1-
induced megakaryocyte migration and platelet production is dependent on matrix metalloproteinases. Blood, 2000,
96:4152-4159.

Hattori K, Heissig B, Tashiro K, Honjo T, Tateno M, Shieh J-H, Hackett N, Quitoriano MS, Crystal RG, Rafii S, Moore MAS.
Plasma elevation of stromal derived factor-1 induces mobilization of mature and immature hematopoietic progenitor
and stem cells. Blood, 2001, 97:3354-3360.

Moore MAS. The role of chemoattraction in cancer metastases. BioEssays, 2001;23:674-676.

Moore MAS, Hattori K, Heissig B, Shieh J-H, Dias S, Crystal RG, Rafii S. Mobilization of endothelial and hematopoietic
stem and progenitor cells by adenovector-mediated elevation of serum levels of SDF-1, VEGF and Angiopoietin. Annals
NY Acad Sci, 2001, 938:36-45.

Perez LE, Alpdogan O, Shieh J-H, Wong D, Merzouk A, Salari H, O'Reilly RJ, Crystal R, van den Brink M, Moore MAS.
Increased plasma levels of stromal derived factor-1 (SDF-1/CXCL12) enhance human thrombopoiesis and mobilize
human colony forming cells (CFC) in NOD/SCID mice. Exp Hematology 2004. 32:300-307.

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