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Lipid Pathogenesis Determinants of M. tuberculosis
Selected Publications
Glickman MS, Cox JS, Jacobs WR Jr. A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis. Mol Cell. 2000 Apr;5(4):717-27.
Glickman MS, Cahill SM, Jacobs WR Jr. The Mycobacterium tuberculosis cmaA2 gene encodes a mycolic acid trans-cyclopropane synthetase. J Biol Chem. 2001 Jan 19;276(3):2228-33.
Glickman MS, Jacobs WR Jr. Microbial pathogenesis of Mycobacterium tuberculosis: dawn of a discipline. Cell. 2001 Feb 23;104(4):477-85.
Huang CC, Smith CV, Glickman MS, Jacobs WR Jr, Sacchettini J. Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis. J Biol Chem. 2002 Mar 29;277(13):11559-69.
Glickman MS. The mmaA2 gene of Mycobacterium tuberculosis encodes the distal cyclopropane synthase of the alpha-mycolic acid.J Biol Chem. 2003 Mar 7;278(10):7844-9.
Otero J, Jacobs WR Jr, Glickman MS.Efficient allelic exchange and transposon mutagenesis in Mycobacterium avium by specialized transduction. Appl Environ Microbiol. 2003 Sep;69(9):5039-44.
Rao V, Fujiwara N, Porcelli SA, Glickman MS. Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule. J Exp Med. 2005 Feb 21;201(4):535-43.
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