Major Research Areas
Research Programs
Cancer Biology & Genetics
Cell Biology
Raju Chaganti
Hironori Funabiki @ Rockefeller.edu
Filippo Giancotti
Alan Hall
Xuejun Jiang
Jidong Liu
Paul A. Marks
Malcolm Moore
Michael Overholtzer
Marilyn Resh
Urs Rutishauser
Timothy A. Ryan @ Cornell.edu
Meng-Fu Bryan Tsou
Computational Biology
Developmental Biology
Immunology
Molecular Biology
Molecular Pharmacology & Chemistry
Structural Biology
Postdoctoral Training
Graduate Education
Summer Undergraduate Research Program
Core Facilities
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Sloan-Kettering Institute
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Research Programs
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Cell Biology
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Filippo Giancotti
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Projects
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Specificity and Complexity of Integrin Signaling
Selected Publications
Wary KK, Mainiero F, Isakoff S, Marcantonio EE, Giancotti FG. The adaptor protein Shc couples a class of integrins to the control of cell cycle progression.
Cell
1996; 87:733-743.
Pozzi A, Wary KK, Giancotti FG, Gardner HA. Integrin alpha1beta1 mediates a unique collagen dependent proliferation pathway in vivo.
J. Cell Biol.
1998; 142:587-594.
Wary KK, Mariotti A, Zurzolo C, Giancotti FG. A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth.
Cell
1998; 94:625-634.
Oktay M, Wary KK, Dans M, Birge RB, Giancotti FG. Integrin-mediated activation of FAK is required for signaling to JNK and progression through the G1 phase of the cell cycle.
J. Cell Biol.
1999; 145:1461-1469.
Barberis L, Wary, KK, Liu, F, Hirsch, E, Brancaccio, M, Altruda, F, Tarone, G, Giancotti, FG. Distinct roles of the adaptor protein Shc and Focal Adhesion Kinase in integrin signaling to ERK.
J. Biol. Chem.
2000, 275:36532-36540.
Mettouchi A, Klein S, Guo W, Lopez-Lago M, Lemichez E, Westwick JK, Giancotti FG. Integrin-specific activation of Rac controls progression through the G(1) phase of the cell cycle.
Mol. Cell
, 2001, 8:115-127.
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