Major Research Areas

Selected Publications

Wary KK, Mainiero F, Isakoff S, Marcantonio EE, Giancotti FG. The adaptor protein Shc couples a class of integrins to the control of cell cycle progression. Cell 1996; 87:733-743.

Pozzi A, Wary KK, Giancotti FG, Gardner HA. Integrin α1β1 mediates a unique collagen dependent proliferation pathway in vivo. J. Cell Biol. 1998; 142:587-594.

Wary KK, Mariotti A, Zurzolo C, Giancotti FG. A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell 1998; 94:625-634.

Oktay M, Wary KK, Dans M, Birge RB, Giancotti FG. Integrin-mediated activation of FAK is required for signaling to JNK and progression through the G1 phase of the cell cycle. J. Cell Biol. 1999; 145:1461-1469.

Barberis L, Wary, KK, Liu, F, Hirsch, E, Brancaccio, M, Altruda, F, Tarone, G, Giancotti, FG. Distinct roles of the adaptor protein Shc and Focal Adhesion Kinase in integrin signaling to ERK. J. Biol. Chem. 2000, 275:36532-36540.

Mettouchi A, Klein S, Guo W, Lopez-Lago M, Lemichez E, Westwick JK, Giancotti FG. Integrin-specific activation of Rac controls progression through the G(1) phase of the cell cycle. Mol. Cell, 2001, 8:115-127.

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