Research Programs Cancer Biology & Genetics Cell Biology Raju Chaganti Hironori Funabiki @ Rockefeller.edu Filippo Giancotti Alan Hall Xuejun Jiang Jidong Liu Paul A. Marks Malcolm Moore Michael Overholtzer Marilyn Resh Urs Rutishauser Timothy A. Ryan @ Cornell.edu Meng-Fu Bryan Tsou Computational Biology Developmental Biology Immunology Molecular Biology Molecular Pharmacology & Chemistry Structural Biology Postdoctoral Training Graduate Education Summer Undergraduate Research Program Core Facilities Collaborative Research Centers Sloan-Kettering Institute > Research Programs > Cell Biology > Filippo Giancotti > Projects > Integrin Signaling during Tumor Invasion and Angiogenesis Selected Publications 46. Mariotti A, Kedeshian P, Dans M, Curatola AM, Gagnoux-Palacios L, Giancotti FG. EGF-R signaling through Fyn kinase disrupts the function of integrin a6b4 at hemidesmosomes: Role in epithelial cell migration and carcinoma invasion. J. Cell Biol., 2001, 155:447-458. Klein S, de Fougerolles AR, Blaikie P, Khan L, Pepe A, Green CD, Koteliansky V, Giancotti FG. The a5b1 integrin activates a NF-kB-dependent program of gene expression important for angiogenesis and inflammation. Mol. Cell. Biol. 2002, 22:5912-5922 Nikolopoulos SN, Blaikie P, Yoshioka T, Guo W, Giancotti FG. Integrin b4 signaling promotes tumor angiogenis. Cancer Cell, 2004, 6:471-483.

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