Major Research Areas

Publications

Parathath SR, Mainwaring LA, Fernandez-L A, Campbell DO, and Kenney AM. Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors. Development, In press.

Knoepfler, PS and Kenney, AM. Neural precursor cycling at sonic speed: N-myc pedals, GSK-3 brakes. Cell Cycle 2006 Jan; 5: 47-51.

Browd S*, Kenney A*, Gottfried O, Yoon J, Walterhouse D, Pedone C, et al. N-myc can substitute for Insulin-like growth factor in a mouse model of Sonic hedgehog-induced medulloblastoma. Cancer Research 2006 Mar 1; 66:2666-72. (* indicates co-first authors)

Sjostrom, SK, Finn, G, Hann, WC, Rowitch, DH, and Kenney, AM. The cdk1 complex plays a prime role in regulating N-myc phosphorylation and turnover in neural precursors. Dev Cell. 2005 Sep;9(3):327-38.

Kenney, AM, Widlund, HR, and Rowitch, DH. Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors. Development. 2004 Jan;131(1):217-28. Epub 2003 Dec 3. Erratum in: Development. 2004 Jan;131(2):489.

Kenney, AM, Cole MD, and Rowitch, DH. Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors. Development. 2003 Jan;130(1):15-28.

Kenney, AM and Rowitch, DH. Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors. Mol Cell Biol. 2000 Dec;20(23):9055-67.

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