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[ 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2002 |
postdoc | grad | undergrad ]
Independent Publications
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26)
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Liu, G.; Wurst, J. M.; Tan, D. S.* "Stereoselective synthesis of benzannulated spiroketals: Influence of the aromatic ring on reactivity and conformation." Org. Lett. 2009, 11, 3670–3673.
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25)
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Lu, X.; Zhang, H.; Tonge, P. J.*; Tan, D. S.* "Mechanism-based inhibitors of MenE, an acyl-CoA synthetase involved in bacterial menaquinone biosynthesis." Bioorg. Med. Chem. Lett. 2008, 18, 5963–5966.
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24)
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Cisar, J. S.; Tan, D. S.* "Small molecule inhibition of microbial natural product biosynthesis – An emerging antibiotic strategy." Chem. Soc. Rev. 2008, 37, 1320–1329.
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23)
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Ferreras, J. A.; Stirrett, K. L.; Lu, X.; Ryu, J.-S.; Soll, C. E.; Tan, D. S.; Quadri, L. E. N.* "Mycobacterial phenolic glycolipid virulence factor biosynthesis: Mechanism and small-molecule inhibition of polyketide chain initiation." Chem. Biol. 2008, 15, 51–61.
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Highlighted in Chemistry & Biology
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22)
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Cisar, J. S.; Ferreras, J. A.; Soni, R. K.; Quadri, L. E. N.*; Tan, D. S.* "Exploiting ligand conformation in selective inhibition of non-ribosomal peptide synthetase amino acid adenylation with designed macrocyclic small molecules." J. Am. Chem. Soc. 2007, 129, 7752–7753.
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Highlighted in Faculty of 1000 Biology
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21)
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Shang, S.; Iwadare, H.; Macks, D. E.; Ambrosini, L. M.; Tan, D. S.* "A unified synthetic approach to polyketides having both skeletal and stereochemical diversity." Org. Lett. 2007, 9, 1895–1898.
[ Abstract | PDF | Supporting Info | PMC ]
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20)
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Moilanen, S. B.; Potuzak, J. S.; Tan, D. S.* "Stereocontrolled synthesis of spiroketals via Ti(Oi-Pr)4-mediated kinetic spirocyclization of glycal epoxides with retention of configuration." J. Am. Chem. Soc. 2006, 128, 1792–1793.
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Highlighted in Nature
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19)
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Potuzak, J. S.; Moilanen, S. B.; Tan, D. S.* "Stereocontrolled synthesis of spiroketals via a remarkable methanol-induced kinetic spirocyclization reaction." J. Am. Chem. Soc. 2005, 127, 13796–13797.
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18)
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Tan, D. S.* "Diversity-oriented synthesis: Exploring the intersections between chemistry and biology." Nature Chem. Biol. 2005, 1, 74–84.
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Highlighted in Nature Chemical Biology
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17)
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Ferreras, J. A.; Ryu, J.-S.; Di Lello, F.; Tan, D. S.*, Quadri, L. E. N.* "Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis." Nature Chem. Biol. 2005, 1, 29–32.
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Highlighted in Nature, Nature Chemical Biology, Chemical & Engineering News, and Mercosur Económico (PDF)
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16)
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Shang, S.; Tan, D. S.* "Advancing chemistry and biology through diversity-oriented synthesis of natural product-like libraries." Curr. Opin. Chem. Biol. 2005, 9, 248–258.
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14)
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Moilanen, S. B.; Tan, D. S.* "Enantioselective synthesis of erythro-4-deoxyglycals as scaffolds for target- and diversity-oriented synthesis: New insights into glycal reactivity." Org. Biomol. Chem. 2005, 3, 798–803.
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13)
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Tan, D. S.* "Current progress in natural product-like libraries for discovery screening." Comb. Chem. High-Throughput Screen. 2004, 7, 631–643.
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12)
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Potuzak, J. S.; Tan, D. S.* "Synthesis of C1-alkyl and C1-acylglycals from glycals using a B-alkyl Suzuki–Miyaura cross coupling approach." Tetrahedron Lett. 2004, 45, 1797–1801.
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11)
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Potuzak, J. S.; Moilanen, S. B.; Tan, D. S.* "Discovery and applications of small molecule probes for studying biological processes." Biotechnol. Genet. Eng. Rev. 2004, 21, 11–78.
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10)
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Tan, D. S.* "Sweet surrender to chemical genetics." Nat. Biotechnol. 2002, 20, 561–563.
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Postdoctoral, Graduate, and Undergraduate Publications
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9)
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Mandal, M.; Yun, H.; Dudley, G. B.; Lin, S.; Tan, D. S.; Danishefsky, S. J.* "Total synthesis of guanacastepene A: A route to enantiomeric control." J. Org. Chem. 2005, 70, in press; doi: 10.1021/jo051470k.
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Featured on the cover.
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8)
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Tan, D. S.; Dudley, G. B; Danishefsky, S. J.* "Synthesis of the functionalized tricyclic skeleton of guanacastepene A: A tandem epoxide-opening β-elimination/Knoevenagel cyclization." Angew. Chem. Int. Ed. 2002, 41, 2185–2188.
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7)
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Lin, S.; Dudley, G. B.; Tan, D. S.; Danishefsky, S. J.* "A stereoselective route to guanacastepene A through a surprising epoxidation." Angew. Chem. Int. Ed. 2002, 41, 2188–2191.
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6)
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Dudley, G. B.; Tan, D. S.; Kim, G.; Tanski, J. M.; Danishefsky, S. J.* "Remarkable stereoselectivity in the alkylation of a hydroazulenone: Progress toward the total synthesis of guanacastepene." Tetrahedron Lett. 2001, 42, 6789–6791.
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5)
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Tan, D. S.; Schreiber, S. L.* "A mercury-catalyzed transetherification cyclization leading to fused cyclic polyethers." Tetrahedron Lett. 2000, 41, 9509–9513.
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4)
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Tan, D. S.*; Burbaum, J. J.* "Ligand discovery using encoded combinatorial libraries." Curr. Opin. Drug Discovery Dev. 2000, 3, 439–453.
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3)
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Tan, D. S.; Foley, M. A.; Stockwell, B. R.; Shair, M. D.; Schreiber, S. L.* "Synthesis and preliminary evaluation of a library of polycyclic small molecules for use in chemical genetic assays." J. Am. Chem. Soc. 1999, 121, 9073–9087.
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2)
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Tan, D. S.; Foley, M. A.; Shair, M. D.; Schreiber, S. L.* "Stereoselective synthesis of over two million compounds having structural features both reminiscent of natural products and compatible with miniaturized cell-based assays." J. Am. Chem. Soc. 1998, 120, 8565–8566.
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Highlighted in Science, Chemical & Engineering News
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1)
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Tan, D. S.; Günter, M. M.; Drueckhammer, D. G.* "Enzymatic resolution coupled with substrate racemization using a thioester substrate." J. Am. Chem. Soc. 1995, 117, 9093–9094.
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