Major Research Areas

Publications

Basu U+, Chaudhuri J+,, Alpert C, Dutt S, Ranganath S, Li G, Schrum JP, Manis JP, Alt FW. (2005) The AID antibody
diversification enzyme is regulated by protein kinase A phosphorylation. Nature. 438(7067):508-11. (+ equal
contributions)

Chaudhuri J, Khuong C, and Alt FW. (2004) Replication Protein A interacts with AID to promote deamination of somatic hypermutation targets. Nature, 430: 992-998.

Chaudhuri J, Tian M, Khuong C, Pinaud E, Alt FW. (2003) Transcription-targeted DNA deamination by the AID antibody diversification enzyme. Nature, 422:726-730.

Chaudhuri J and Alt FW. (2004) Class Switch Recombination: Interplay of transcription, DNA deamination and DNA repair. Nature Reviews Immunology. 4: 541-52

Zarrin AA, Alt FW, Chaudhuri J, Stokes N, Kaushal D, Du Pasquier L and Tian M. (2005) An evolutionarily conserved target motif for immunoglobulin class-switch recombination. Nat Immunol, 5:1275-1281.

Dudley DD, Chaudhuri J, Bassing CH, Alt FW (2005) Mechanism and Control of V(D)J Recombination versus Class Switch Recombination: Similarities and Differences. Adv Immunol, 86: 43-112.

Rooney S, Chaudhuri J, and Alt FW. (2004) The role of the non-homologous end-joining pathway in lymphocyte development. Immunological Reviews. 200: 115-131.

Dedeoglu F, Horwitz B, Chaudhuri J, Alt FW, Geha RS. (2004) Induction of AID gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkB. Int. Immunol. 16: 395-404.

Gao Y, Chaudhuri J, Zhu C, Davidson L, Weaver DT, Alt FW. (1998) A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU
in V(D)J recombination. Immunity. 9:367-76.

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