Current Research Interests:
Dr. Qin's research interests are in statistical genomics and cancer genomics. She has been developing statistical methods for data normalization, gene clustering, sample clustering, and sample classification, focusing primarily on gene expression data, and methods to integrate information from multiple types of genomic data.
Dr. Qin is involved in genomic collaborations from a number of disease areas, such as soft tissue sarcoma, neuroblastoma, ovarian cancer, and colon cancer. She is also responsible for the design and analysis of clinical trials and retrospective studies in soft tissue sarcoma.
Selected Bibliography:
- Qin LX and Satagopan J. Normalization method for transcriptional studies of heterogeneous samples - simultaneous array normalization and identification of equivalent expression. Statistical Applications in Genetics and Molecular Biology 2008, 8: Article 10. [bepress Abstract]
- Qin LX. An Integrative Analysis of microRNA and mRNA Expression - A Case Study. Cancer Informatics 2008, 6:369-379.
- Qin LX and Self SG. The clustering of regression models method with applications to gene expression data. Biometrics 2006, 62: 526-533. [PubMed Abstract]
- Qin LX, Beyer R, Hudson N, Linford N, Morris D, Kerr KF. Validation of data transformation methods for oligonucleotide arrays with qRT-PCR measurements. BMC Bioinformatics 2006, 7:23. [PubMed Abstract]
- Qin LX, Kerr KF, Contributing Members of the Toxicogenomics Research Consortium. Empirical evaluation of data transformations and ranking statistics for microarray analysis. Nucleic Acids Research 2004, 32(18):5471-5479. [PubMed Abstract]
