Information about Ethan Basch's clinical work and patient appointment availability.
Current Research Interests:
Dr. Basch'sresearch focuses on the use of patient reported outcomes (PROs) to assess drug toxicity and symptom endpoints in cancer treatment trials. He was awarded a 2-year, 1.8 million NCI contract to create a patient version of the standard lexicon for adverse event reporting in oncology trials, the Common Terminology Criteria for Adverse Events (CTCAE). This project involves coordination of investigators at five participating cancer centers, and three national clinical trials. He reported results of a study measuring the relationship between toxicity reporting and survival in presentations at the annual meeting of the American Society of Clinical Oncology (ASCO) and at the NCI. Dr. Basch is currently Principal Investigator of two MSKCC protocols and Chair of a multi-center study through the NCI cooperative group, the CALGB (Cancer and Leukemia Group B). Other funding support for this work includes an ASCO Career Development Award and NCI K07 award. He continues to contribute to the debate over the patient's role in toxicity monitoring through committee work at ASCO, ISPOR, and as a formal advisor to the FDA Study Endpoints division. Dr. Basch's related informatics work focuses on improvement of data standards, in his roles as informatics director for the Department of Defense's Prostate Cancer Clinical Trials Consortium, and as director of the new MSKCC Core service for online research surveys.
Selected Publications:
- Basch E, Iasonos A, McDonough T, Barz A, Culkin A, Kris MG, Scher HI, Schrag D. Clinician versus patient self-reporting of symptoms during cancer treatment: a paired analysis using the National Cancer Institute's Common Terminology Criteria for Adverse Events (CTCAE). Lancet Oncol, 2006;7(10): 903-909.
- Basch E, Artz D, Dulko D, Scher K, Sabbatini P, Hensley M, Mitra N, Speakman J, McCabe M, Schrag D. Patient online self-reporting of toxicity symptoms during chemotherapy. J Clin Oncol 2005;23(15):3552-61.
- Basch EM, Thaler HT, Shi W, Yakren S, Schrag D. Use of information resources by patients with cancer and their companions. Cancer 2004;100(11):2476-83.
- Basch EM, Servoss JC, Tedrow UB. Safety assurances for dietary supplements policy issues and new research paradigms. J Herb Pharmacother 2005;5(1):3-15.
- Basch EM, Bonfiglio MF. Pharmaceutical manufacturer sponsorship and drug information. Archives of Internal Medicine 2001;161:2625-2526.
