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Find a Clinical Trial
Find a Clinical Trial
Find out about new research studies for prostate cancer

Investigational approaches are sometimes offered to eligible patients through the clinical trial process. Clinical trials are designed to improve upon the current standards of care in each clinical state.

Like all cancer treatments at Memorial Sloan-Kettering, these clinical trials involve a team approach, as scientists, radiologists, pathologists, and other clinicians work together to care for each patient. Patients on clinical trials are still under the care of their primary provider at Memorial Sloan-Kettering, but the expertise of the physicians and scientists who are involved with the trial are often called upon. Our expertise is in determining which patients will derive the most benefit from which trial -- whether it is of chemotherapy, immune therapy, or biologic therapy, or a combination of approaches, the basis of many clinical trials here. These research programs are updated continuously. For up-to-date information about the Urology Department's clinical trials, please visit our clinical trial database.

Physicians from three clinical disciplines -- surgery, medical oncology, and radiation oncology -- are all involved in the care of every prostate cancer patient here at every phase of the disease. Behind the scenes, our expert radiologists and pathologists are also involved. This collaborative approach ensures that each patient receives the treatment most suited to his particular condition and circumstances. Higher-risk patients treated at Memorial Sloan-Kettering have unique access to clinical trials, in which research protocols studying investigational approaches are offered to eligible patients. Patients who qualify and choose treatment through a clinical trial will find that the principal investigators of many national trials are here, and these doctors oversee their care throughout their course of treatment.

Sidney Kimmel Center for Prostate & Urologic Cancers
Sidney Kimmel Center for Prostate & Urologic Cancers
Our state-of-the-art
outpatient
facility offers
comprehensive care

A host of new treatments that build on chemotherapies and on our understanding of the disease are under investigation at Memorial Sloan-Kettering, and our group has led the national effort on the best ways to conduct these trials. Approaches include new chemotherapies, drugs that target the mechanisms that stimulate cancer growth, agents that specifically target prostate cancer cells in bone, and methods of harnessing the immune system to recognize and attack the cancer. We are also exploring new, noninvasive methods of defining the biology of a patient's prostate cancer, using novel imaging techniques. Our group will guide the patient through the often confusing process of choosing a clinical trial based on his lifestyle, medical needs, and the biology of his disease.

Trials for patients with localized disease are designed to determine ways to enhance potency and continence. For patients with high-risk localized disease, trials are designed to find ways to enhance the rate of cure following surgery or radiation. Such approaches include adding chemotherapy with hormonal therapy to radiation or surgery. For patients who have a rising PSA following surgery or radiation and who are at risk of developing metastases, trials are designed to prevent the onset of detectable disease in bone. These strategies may involve novel hormonal approaches, chemotherapy, and vaccine therapy. For patients with newly detected metastases, trials are designed to improve on standard hormonal treatments. For patients with metastases that have progressed in spite of hormones, trials are designed to prolong life and enhance quality of life. These trials build on existing chemotherapy regimens, develop new approaches that inhibit the biologic pathways that drive tumor growth and dissemination, and explore ways to target cancer cells while sparing normal tissues.


Last Updated: Dec. 9, 2005
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