Major Research Areas

Publications

Olshen AB, Gold B, Lohmueller KE, Struewing JP, Satagopan J, Stefanov SA, Eskin E, Kirchhoff T, Lautenberger JA, Klein RJ, Friedman E, Norton L, Ellis NA, Viale A, Lee CS, Borgen PI, Clark AG, Offit K, Boyd J. Analysis of genetic variation in Ashkenazi Jews by high density SNP genotyping. BMC Genet. 2008 Feb 5;9:14.

Gold B, Kirchhoff T, Stefanov S, Lautenberger J, Viale A, Garber J, Friedman E, Narod S, Olshen AB, Gregersen P, Kosarin K, Olsh A, Bergeron J, Ellis NA, Klein RJ, Clark AG, Norton L, Dean M, Boyd J, Offit K. Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4340-5. Epub 2008 Mar 7.

Klein RJ. Power analysis for genome-wide association studies. BMC Genet. 2007 Aug 28; 8:58.

Zareparsi S, Branham KE, Li M, Shah S, Klein RJ, Ott J, Hoh J, Abecasis GR, Swaroop A. Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration. Am J Hum Genet. 2005 Jul;77(1):149-53.

Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J. Complement factor H polymorphism in age-related macular degeneration. Science. 2005 Apr 15;308(5720):385-9.

Kim H, Klein R, Majewski J, Ott J. Estimating rates of alternative splicing in mammals and invertebrates. Nat Genet 2004 Sep;36(9):915-6.

Klein RJ, Eddy SR. RSEARCH: finding homologs of single structured RNA sequences. BMC Bioinformatics. 2003 Sep 22;4:44.

Klein RJ, Misulovin Z, Eddy SR. Noncoding RNA genes identified in AT-rich hyperthermophiles. Proc Natl Acad Sci U.S.A. 2002 May 28;99(11):7542-7.

Rivas E, Klein RJ, Jones TA, Eddy SR. Computational identification of noncoding RNAs in E. coli by comparative genomics. Curr Biol. 2001 Sep 4;11(17):1369-73.

de Souza SJ, Long M, Klein RJ, Roy S, Lin S, Gilbert W. Toward a resolution of the introns early/late debate: only phase zero introns are correlated with the structure of ancient proteins. Proc Natl Acad Sci U.S.A. 1998 Apr 28;95(9):5094-9.

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