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Clinical Trials

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Bladder Cancer
Germ Cell Tumors
Kidney Cancer
Prostate Cancer

A 12-Gene Blood-Based Signature for Detecting Metastatic Bladder Cancer
Dalbagni, Guido, MD

[Protocol 09-054]
A Genotype-Phenotype Urothelial Cancer Study
Bajorin, Dean, MD

[Protocol 09-025]
A Phase II Study of Everolimus (RAD001) in Metastatic Transitional Cell Carcinoma of the Urothelium
Milowsky, Matthew, MD

[Protocol 08-123]
A Phase II Study of Gemcitabine, Cisplatin, and Sunitinib as Chemotherapy Before Surgery in Patients with Muscle-Invasive Bladder Cancer
Bajorin, Dean, MD

[Protocol 08-159]
A Phase II Trial of Gemcitabine and Cisplatin plus Sorafenib in Chemotherapy-naïve Patients with Locally Advanced or Metastatic Urothelial Carcinoma
Milowsky, Matthew, MD

[Protocol 07-168]
A Phase II Trial of Gemcitabine, Carboplatin, and Bevacizumab in Chemotherapy-naïve Patients with Advanced/Metastatic Urothelial Carcinoma
Bajorin, Dean, MD

[Protocol 06-006]
A Phase III Study of Mitomycin C versus Bacillus Calmette-Guerin in the Intravesical Treatment of Non-Muscle-Invasive Bladder Cancer
Dalbagni, Guido, MD

[Protocol 09-118]
A Prospective Study of Quality of Life in Patients Undergoing Pelvic Exenteration
Chi, Dennis, MD

[Protocol 05-001]
A Prospective Study of Quality of Life in Patients with Invasive Bladder Cancer
Bochner, Bernard, MD

[Protocol 08-076]
A Survey of Penile Injection Anxiety
Nelson, Christian, PhD

[Protocol 07-001]

Germ Cell Tumors

A Phase I Trial of Sequential Paclitaxel/Ifosfamide and Dose-Intensive Paclitaxel, Carboplatin, and Dose-Escalated Ifosfamide with Stem Cell Support in Cisplatin- Resistant Germ Cell Tumor Patients
Feldman, Darren, MD

[Protocol 06-077]
A Phase II Study of Bevacizumab for Recurrent Malignant Stromal Tumors of the Ovary
Leitao, Mario, MD

[Protocol 09-062]
A Phase II Study of Flavopiridol Plus Oxaliplatin with or without 5-FU and Leucovorin for Relapsed or Refractory Germ-Cell Tumors
Feldman, Darren, MD

[Protocol 09-034]
Evaluating the Causes of Cancer in Young Patients
Stadler, Zsofia, MD

[Protocol 09-068]
Phase II Trial of Paclitaxel, Ifosfamide, and Cisplatin in Patients with Previously Untreated Advanced Germ Cell Tumors
Feldman, Darren, MD

[Protocol 07-044]

A Genotype-Phenotype Urothelial Cancer Study
Bajorin, Dean, MD

[Protocol 09-025]
A Phase I Study of AGS-16M18 in Patients with Advanced Renal Cell Carcinoma
Kroog, Glenn, MD

[Protocol 08-086]
A Phase I Study of MDX1411 in Patients with Advanced or Recurrent Clear Cell Renal Cell Carcinoma
Kroog, Glenn, MD

[Protocol 08-029]
A Phase I Study of Yttrium-90 Attached to Chimeric Monoclonal Antibody CG250 in Patients with Advanced Renal Cancer
Larson, Steven, MD

[Protocol 05-031]
A Phase II Study of RAD001 and Sunitinib for the Treatment of Patients with Metastatic Renal Cell Carcinoma
Motzer, Robert, MD

[Protocol 09-113]
A Phase III Study of Adjuvant Sunitinib versus Placebo in Patients with High-Risk Renal Cell Carcinoma
Motzer, Robert, MD

[Protocol 07-086]
A Phase III Study of Axitinib versus Sorafenib as Second-line Therapy for Metastatic Renal Cell Cancer: the AXIS trial
Motzer, Robert, MD

[Protocol 08-059]
A Study of Pazopanib versus Sunitinib for the Treatment of Patients with Locally Advanced and/or Metastatic Renal Cell Carcinoma
Motzer, Robert, MD

[Protocol 08-089]
A Study of Temsirolimus and Sorafenib as Second-Line Therapy in Patients with Advanced Renal Cell Carcinoma that Has Grown Despite First-Line Sunitinib Therapy
Motzer, Robert, MD

[Protocol 07-124]

Prostate Cancer

2-[¹⁸F]-Deoxy-D-Glucose (FDG) and [¹⁸F] Dihydro-Testosterone PET Imaging in Patients with Progressive Prostate Cancer
Morris, Michael, MD

[Protocol 00-095]
A Phase I Dose Escalation Study Using Ultra-Hypofractionated, Image-Guided, Intensity-Modulated Radiotherapy in Prostate Cancer
Cox, Brett, MD

[Protocol 09-035]
A Phase I Study of Vaccine Replicon Particles (VRP) Expressing Prostate-Specific Membrane Antigen (PSMA) in Patients with Prostate Cancer
Slovin, Susan, MD, PhD

[Protocol 08-028]
A Phase I/II Study of HE3235 in Patients with Prostate Cancer
Morris, Michael, MD

[Protocol 08-090]
A Phase II Study of Focal Cryoablation in Low-Risk Prostate Cancer
Eastham, James, MD

[Protocol 08-118]
A Phase II Study of IMC-A12 or IMC-1121B Plus Mitoxantrone and Prednisone in Metastatic Androgen-Independent Prostate Cancer Following Disease Progression on Docetaxel-Based Chemotherapy
Rathkopf, Dana, MD, PhD

[Protocol 08-102]
A Phase II Study of Short-Course Androgen Deprivation (Hormonal) Therapy with or without Bevacizumab for PSA Recurrence of Prostate Cancer after Definitive Local Therapy
Slovin, Susan, MD, PhD

[Protocol 09-123]
A Phase II Trial of Exogenous Testosterone Plus Dutasteride for the Treatment of Castrate Metastatic Prostate Cancer
Morris, Michael, MD

[Protocol 09-008]
A Phase III Study of Abiraterone Acetate Plus Prednisone in Men with Metastatic Castration-Resistant Prostate Cancer
Rathkopf, Dana, MD, PhD

[Protocol 09-032]
A Phase III Study of Androgen Deprivation with Leuprolide with or without Docetaxel for Clinically Asymptomatic Prostate Cancer Patients with a Rising PSA Following Surgery
Morris, Michael, MD

[Protocol 07-101]
A Phase III Study of Docetaxel with and without Dasatinib in Castration-Resistant Prostate Cancer
Morris, Michael, MD

[Protocol 09-050]
A Phase III Study of Early Versus Standard Zoledronic Acid to Prevent Bone Problems in Men with Prostate Cancer that Has Spread to the Bone
Morris, Michael, MD

[Protocol 06-091]
A Phase III Study of Neo-Adjuvant Docetaxel and Androgen Deprivation versus Immediate Radical Prostatectomy in Patients with High-Risk, Clinically Localized Prostate Cancer
Eastham, James, MD

[Protocol 07-041]
A Phase III Trial of Short-Term Androgen Deprivation with Pelvic Lymph Node or Prostate Bed-Only Radiotherapy in Prostate Cancer Patients with a Rising PSA after Radical Prostatectomy
Zelefsky, Michael, MD

[Protocol 09-102]
A Phase Ib Study of MDX-1106 in Patients with Selected Advanced or Recurrent Malignancies
Wolchok, Jedd, MD, PhD

[Protocol 09-012]
A Phase Ib Study of Panobinostat (LBH589) with Docetaxel and Prednisone in Patients with Hormone-Refractory Prostate Cancer
Rathkopf, Dana, MD, PhD

[Protocol 07-163]
A Pilot Study of High Dose-Rate Prostate Brachytherapy as Salvage Therapy for Locally Recurrent Prostate Cancer Previously Treated with External Beam Radiotherapy
Yamada, Yoshiya, MD

[Protocol 06-122]
A Pilot Study of High-Dose Rate Brachytherapy as Definitive Management for Intermediate Risk Prostate Cancer
Yamada, Yoshiya, MD

[Protocol 07-120]
A Randomized Trial of Pharmacological Penile Rehabilitation in the Preservation of Erectile Function Following Bilateral Nerve-Sparing Radical Prostatectomy
Mulhall, John, MD

[Protocol 09-005]
A Study of Avanafil for the Treatment of Erectile Dysfunction Following Bilateral Nerve-Sparing Radical Prostatectomy
Mulhall, John, MD

[Protocol 09-064]
A Survey of Penile Injection Anxiety
Nelson, Christian, PhD

[Protocol 07-001]
Assessing the Change in Penile Length Following Bilateral Nerve-Sparing Radical Prostatectomy
Mulhall, John, MD

[Protocol 08-135]
Clinical Significance of Germline BRCA Mutations
Offit, Kenneth, MD

[Protocol 96-051]
High Intensity Focused Ultrasound for the Treatment of Low-Risk, Localized Prostate Cancer
Eastham, James, MD

[Protocol 08-016]
Longitudinal Assessment of Health-Related Quality of Life in Men with Localized Prostate Cancer
Scardino, Peter, MD

[Protocol 02-042]
Neoadjuvant Hormonal Therapy in Combination with Vorinostat Followed by Radical Prostatectomy for Localized Prostate Cancer
Slovin, Susan, MD, PhD

[Protocol 06-160]
Phase I Study of Alpharadin^TM in Patients with Hormone-Refractory Prostate Cancer and Skeletal Metastases
Morris, Michael, MD

[Protocol 08-058]
Phase II Prospective Trial of Vaccine Responses Against Pneumococcus and Influenza in Adult Cancer Patients Age 65 and Older
Small, Trudy, MD

[Protocol 08-005]
Pilot Study of a Geriatric-Specific Psychoeducational Intervention for Elderly Cancer Patients
Roth, Andrew, MD

[Protocol 09-116]
Radiotherapy Plus Sildenafil (Viagra) to Preserve Erectile Function Versus Radiotherapy Alone in Localized Prostate Cancer
Zelefsky, Michael, MD

[Protocol 05-007]
Serum Protein Profiling to Characterize Patient Risk in Men Undergoing Radical Prostatectomy
Eastham, James, MD

[Protocol 04-132]
The Impact of Androgen Ablation Therapy on Cognitive Functioning and Functional Status in Men with Prostate Cancer Age 65 and Older
Nelson, Christian, PhD

[Protocol 06-084]

Germ Cell

A Phase I Trial of Sequential Paclitaxel/Ifosfamide and Dose-Intensive Paclitaxel, Carboplatin, and Dose-Escalated Ifosfamide with Stem Cell Support in Cisplatin- Resistant Germ Cell Tumor Patients
Feldman, Darren, MD

[Protocol 06-077]
Phase II Trial of Paclitaxel, Ifosfamide, and Cisplatin in Patients with Previously Untreated Advanced Germ Cell Tumors
Feldman, Darren, MD

[Protocol 07-044]

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