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Polydox

How It Works

Bottom Line: Polydox (PolyMVA) can not cure or treat cancer, lupus, asthma, HIV, or any other medical condition.

PolyMVA is a product sold on the internet that is said to contain lipoic acid, acetyl cysteine, palladium, B vitamins, and other ingredients. The inventor and promoters of Polydox make many claims for this product, including that it kills cancer cells, that are not supported by any laboratory testing. Some of the components of PolyMVA are antioxidants (alpha-lipoic acid and acetyl cysteine).


Purported Uses

  • To treat asthma
    No scientific evidence supports this use.
  • To treat cancer 
    No scientific evidence supports this use.
  • To treat chronic fatigue syndrome
    No scientific evidence supports this use.
  • To treat HIV and AIDS
    No scientific evidence supports this use.
  • To treat psoriasis
    No scientific evidence supports this use.
  • To treat systemic lupus erythematosus (SLE)
    No scientific evidence supports this use.

  • Research Evidence

    No clinical trials have tested the safety or effectiveness of Polydox for any proposed use.

    Warnings

    • This product is regulated by the FDA as a dietary supplement. Unlike approved drugs, supplements are not required to be manufactured under specific standardized conditions. This product may not contain the labeled amount or may be contaminated. In addition, it may not have been tested for safety or effectiveness.

    Common Name

    LAPd, lipoic acid-palladium complex

    Brand Name

    PolyMVA, POLYDOX

    Clinical Summary

    A synthetic product containing lipoic acid-palladium complex and B complex vitamins. Patients use this supplement to treat cancer, HIV/AIDS, chronic fatigue syndrome, psoriasis, and other degenerative disorders. An animal study suggests Poly MVA may have neuroprotective effect when injected. (3)


    Purported uses

    • Asthma
    • Cancer treatment
    • Chronic fatigue syndrome
    • HIV and AIDS
    • Psoriasis
    • Systemic lupus erythematosus (SLE)

    Constituents

  • Lipoic acid complexed with palladium
  • Vitamins: B12, B-complex
    (1)

  • Mechanism of Action

    The inventor claims that Polydox is a 'metalo-vitamin' with antioxidant activity capable of repairing damaged genes. Polydox is said to have DNA reductase and 'electro-active' properties that alter electron flow in cancer cells at the mitochondrial level, resulting in cytotoxicity. Lipoic acid-palladium complex based product may have neuroprotective effects in animals (3). The manufacturer reports benefits for cancer patients such as increases in energy and appetite, reduction in cancer-related pain. However, no independent scientific data support these claims. Strong antioxidant activity may interfere with the actions of certain chemotherapeutic agents.
    (1) (2)

    Pharmacokinetics

    The manufacturer claims that Polydox distributes throughout the body to all sites, including adipose tissue and the central nervous system. No formal pharmacokinetics studies have been performed.
    (1)

    Adverse Reactions

    Unknown

    Herb-Drug Interactions

    Polydox's antioxidant activity may interfere with the actions of certain chemotherapeutic agents.

    Literature Summary and Critique

    No human studies, case reports, animal studies, or in vitro data have been published.

    References

    1. Polymva. American Medicine and Research Center web site. Available at http://www.polymva.com (accessed September 17, 2007).
    2. Garnett M. Palladium complexes and methods for using same in the treatment of tumors. Garnett McKeen Laboratory, Inc. US Patent #5,679,697. October 21, 1997.
    3. Antonawich FJ, Fiore SM, Welicky LM. Regulation of ischemic cell death by the lipoic acid-palladium complex, Poly MVA, in gerbils. Exp Neurol.2004 Sep;189(1):10-5.

    Last Updated: Sep. 17, 2007
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