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Maureen Zakowski
Maureen Zakowski, Pathologist
"Behind every slide we examine is a patient. . . . And our decisions direct the surgery or chemotherapy a patient will receive. It's an awesome responsibility."

In 2005, pathologist Maureen F. Zakowski became the first female senior attending in the Department of Pathology. While Dr. Zakowski enjoys challenging herself with numerous professional responsibilities, she was confronted with a different sort of challenge when she was diagnosed with endometrial cancer in November 2005.

Growing up in Brooklyn, I was inspired by my mother, who is a nurse, to go into medicine. Early in my studies, my intention was to become a surgeon. But the more I learned, the more I began to realize that surgery as a field -- the nuts and bolts aspect of it -- was not for me. In medical school, I developed an interest in pathology, which I chose for my residency at Hartford Hospital in Connecticut.

After my residency training was completed, I came to Memorial Sloan-Kettering Cancer Center in 1988 for the first of two clinical fellowships in pathology, one in surgical pathology and one in cytopathology. Following this, I accepted a position at New York University Medical Center.

Two years later, the Chair of Pathology asked me to return to Memorial Sloan-Kettering. I was flattered and anxious at the same time. To be honest, I wasn't sure if I could live up to what I considered to be Memorial's high standards, particularly in such a distinguished department as Pathology. Still, unable to pass up such an opportunity, I accepted the offer and started in 1992. I was welcomed back into the extraordinarily demanding environment in the Department of Pathology. The challenge of living up to the Memorial ideal was a wonderful motivator, but the additional challenge of moving beyond still being viewed as a fellow had to be overcome. With the support of David Klimstra, now Chief of the Surgical Pathology Service, and Marc Rosenblum, who is now the department Chair, I expanded my work, which quickly resulted in a number of journal articles in the field of cancer cytopathology and the start of my academic career. I also took over the job of supervising the training of the cytopathology and surgical pathology fellows -- a role that requires a combination of talents: part mentor, part drill sergeant, and part den mother.

As a discipline, pathology provides its own special opportunities and difficulties. Unlike with a surgeon or an oncologist, no patient is ever going to say, "Thanks, Doc," to a pathologist. Patients rarely even know we exist. To be successful, one needs to have an internal sense of gratification, a sense of satisfaction in getting the diagnosis right. Of course, behind every slide we examine is a patient. I remind my clinical fellows that someone is pacing in a waiting room, holding a loved one's hand, waiting nervously as we make our diagnosis. And our decisions direct the surgery or chemotherapy that a patient will receive. It's an awesome responsibility. I insist that my trainees spend time during their training in the clinic setting seeing patients with the oncologists or surgeons. I do it myself as well. While this approach is unusual in pathology, it helps us better understand the patients' needs and adds a personal dimension to the research and collaborative work I do within my team.

Today, my professional responsibilities can be divided into three parts: my clinical diagnostic work in the fields of cytopathology and thoracic pathology, the teaching of fellows, and my academic responsibilities as a member of the Thoracic Disease Management Team (DMT). Additionally, I have the great pleasure to be a member of the Lung Cancer Oncogenome Group, which was created under the leadership of [Memorial Sloan-Kettering President] Harold Varmus to further the development of targeted therapies for lung cancer. Lung cancer remains an underfunded disease, and a great deal of new information regarding therapy is emerging, much of it due to this talented group.

As a member of the Thoracic DMT, a remarkable team led by Mark Kris, Chief of the Thoracic Oncology Service, and Valerie Rusch, Chief of the Thoracic Surgery Service, I have been given the sort of professional opportunity that only comes once in a lifetime -- and it takes place in a highly enjoyable working environment. I tell my clinical fellows that if you aren't enjoying what you're doing, it's not worth coming to work every day.

Unfortunately, I experienced a setback last year when I was diagnosed with endometrial cancer. Fortunately, it was caught early. Once I was diagnosed, there was no question that I would have my treatment at Memorial Hospital. At the risk of sounding corny, if I had to be sick, it felt good to be sick here. Nobody believes me, but the most difficult part of the entire experience -- which ended with my last chemotherapy treatment in April of this year -- was not being able to come into work on a daily basis.

Looking back, what Memorial Sloan-Kettering represented to me when I was a fellow -- a place where the best and brightest come to help patients in need -- still holds true today. I like to believe that what I see under the microscope plays an essential role in helping patients in their own battles with cancer.


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