Joseph Chewning, MD
PI: Bo Dupont, MD
Research Project: Examining the influence of autologous HLA on function of the NK cell activating receptor KIR2DS1.
Stacie Goldberg, MD
PI: Alan Houghton, MD
Research Project: Exploring strategies for inducing the immune system to reject cancer; investigating the potency of DNA, peptide, and viral delivery systems as cancer vaccines both in melanoma and soft tissue sarcomas; and developing several novel therapeutic agents and peptide vaccines for clinical trials.
Matthias Karajannis, MD
PI: Shahin Rafii, MD
Research Project: Examination of the role of proangiogenic factors in leukemia-stroma interactions.
Oren Becher, MD
PI: Eric Holland, MD, PhD
Research Project: Preclinical studies in a genetically engineered model of medulloblastoma.
Sonali Chaudhury, MD
PI: Malcolm Moore, MD
Research Project: Development of in vitro and in vivo experimental models for competitive repopulation in double cord blood transplant -- Role of NK and T cells; development and expansion of NK and T cells from cord blood-derived hematopoietic stem cells.
Sarah Gall, MD
PI: William Gerald, MD
Research Project: EWS-WT1 translocation in Desmoplastic Small Round Cell Tumor: Gene regulation and oncogenesis.
Douglas Harrison, MD
PI: Mary K. Baylies, PhD
Research Project: Examining the role of key Drosophila transcription factors in pediatric tumors.
Rosanna Ricafort, MD
PI: Michel Sadelain, MD
Research Project: Methods permitting sensitization, growth and selection of virus-specific CD4+ T cells for use in adoptive T cell therapies in an effort to develop cellular immunotherapy in the allogeneic stem cell transplant setting, not only for viral diseases such as cytomegalovirus but also against various malignancies as new targets are defined for tumor immunotherapy.
Neal Shukla, MD
PI: Marc Ladanyi, MD
Research Project: Analysis of tyrosine kinases in pediatric sarcomas, including mutation screen of highly expressed kinases, inhibition assays of overexpressed kinases, and analysis of downstream signaling of over expressed kinases.
Aisha Hasan, MD
PI: Richard J. O'Reilly, MD
Research Project: Generation of HLA class I-restricted Cytomegalovirus CMV-specific T cells using artificial antigen presenting cells.
Edward Garmey, MD
PI: Charles Sklar, MD
Research Project: Obesity in Survivors of Childhood Acute Lymphoblastic Leukemia: A Follow-Up Report from the Childhood Cancer Survivor Study; Ethanol-Lock Technique (ETL) for Central Venous Lines with Recurrent or Life-Threatening Infections.
Kathleen O'Day, MD
PI: William Gerald, MD
Research Project: Molecular classification of neuroblastoma by microarray.
Mary Pao, MD, PhD
PI: David Scheinberg, MD
Research Project: Generation of a heteroclitic peptide vaccine against Ewing's Sarcoma; Use of carbon nanotubes to deliver peptide vaccines.
Angeli Rampersad, MD
PI: Katherine Hajjar, MD
Research Project: Delineating the role of the human mast cell and Annexin 2, a profibrinolytic cell surface protein, in atherogenesis and in angiogenesis.
Trisha Tavares, MD
PI: Lorraine Gudas, PhD
Research Project: Examining the different signaling proteins involved in tumors that are responsive to Retinoic Acid and other differentiating agents.
