Pediatric Scientist Development Program (PSDP) Postdoctoral Fellow
Developmental Biology/Joyner Lab, Sloan-Kettering Institute
Memorial Sloan-Kettering Cancer Center
Project: Analysis of Fgf Signaling During Midbrain and Hindbrain Embryogenesis
2003-2006
Chief Fellow, Pediatric Neurology
Children's Hospital, Boston
Harvard Medical School
2001-2003
Resident in Pediatrics
Babies & Children's Hospital of New York
Columbia-Presbyterian Medical Center
1992-2001
M.D., University of Pennsylvania School of Medicine
2000
Ph.D., University of Pennsylvania School of Medicine
Thesis: Identification of SANE, a Novel BMP Inhibitor that Regulates Dorsal-Ventral Patterning During Xenopus laevis Embryogenesis
Advisor: Peter S. Klein, MD, PhD; Howard Hughes Medical Institute
1992
B.A. in Biochemistry, University of Pennsylvania
Publications:
Raju, G. P., Belland, S. E, and Eisen, H. J. (1994) Prolongation of Cardiac Al-lograft Survival with Transforming Growth Factor-ß1 in Rats. Transplantation, 58: 392-396.
Woo, Y. J., Raju, G. P., Gardner, T. J., Balice-Gordon R. J., Swain, J. L. (1996)
In Utero Murine Recombinant Adenoviral Gene Transfer. Surgical Forum, 47: 277-278.
Woo, Y, J., Raju, G. P., Swain, J. L., Richmond, M. E., Gardner, T. J., and Balice-Gordon, R.J. (1997). In Utero Cardiac Gene Transfer Via Intraplacental Delivery of Recombinant Adenovirus. Circulation, 96: 3561-3569.
Raju. G. P., Tan, C., and Klein, P. S. (1999), "Concepts in Early Embryonic Pat-terning" Chapter in Molecular Biology in Reproductive Medicine. ed. BCJM Fauser; Parthenon Publishing Group, New York.
Raju, G. P., Dimova, N., Klein, P. S., and Huang, H. C., SANE, A. (2003). Novel LEM Domain Protein, Regulates BMP Signaling through Interaction with Smad1. Journal of Biological Chemistry. 278(1): 428-37.
Neal, J., Raju, G. P., Bodell, A., Apse, K., Walsh, C. A, and Sheen, V. L., (2006)
Periventricular heterotopia with complete agenesis of the corpus callosum: A case report. Journal of Neurology, 2006: 10:1-3.
Raju, G. P., Urion, D. K., and Sahin, M. (2007). Neonatal Subependymal Giant Cell Astrocytoma: New Case and Review of Literature. Pediatric Neurology, 6: (2): 128-131.
Raju, G. P., Poduri, A., Sarco, D., Riviello, J., Bergin, A. M., Takeoka, M. (2007).
Oxcarbazapine Effective in Nocturnal Frontal Lobe Epilepsy. Submitted to Pediatric Neurology.
Raju, G. P., Li S-C, Bali, D. S, Chen, Y. T, Urion D. K., Lidov H. G. W., Kang, P. B. (2007). Congenital type IV glycogen storage disease with GBE1 mutation: a case report. Manuscript in preparation.
Research Interests:
I am a pediatric neurologist with a research background in signal transduction during embryogenesis using biochemical and molecular biology approaches. I joined Alex's research group as a postdoctoral fellow to learn mouse genetics. I hope to combine my biochemistry experience with the sophisticated mouse tools that are being developed within the Joyner lab to understand mechanisms of early CNS embryogenesis with a focus on signal transduction pathways.
Specifically, I am currently working on the role of FgfR1 in early midbrain and hindbrain patterning using a novel mosaic analysis technique in mouse. In addition, I am also taking advantage of the chick embryo system to biochemically analyze signal transduction mechanisms of Fgf8 and Fgf17.
