Major Research Areas
Developmental Biology
Office Phone:212-639-3980
Office Fax:212-717-3738
E-mail:browneli@mskcc.org

Isaac Brownell
Isaac Brownell, MD, PhD
Postdoctoral Research Fellow

Education and Training:


July 2006-Present


Postdoctoral Research Fellowship. Developmental Biology Program. Sloan-Kettering Institute. Memorial Sloan-Kettering Cancer Center. Principle investigator: Alexandra Joyner, PhD

June 2004-June 2007


Residency (including Sulzberger Research Fellowship). Department of Dermatology. New York University (NYU) School of Medicine.

June 2003-June 2004


Internship. Transitional residency program. Christus St Joseph Hospital. Hous-ton, TX.

August 1995-May 2003


M.D. with Honors. Baylor College of Medicine (BCM). Houston, TX.

July 1997-April 2002


Ph.D. Baylor College of Medicine (BCM). Houston, TX
Department: Molecular and Cellular Biology. Advisor: Milan Jamrich, Ph.D.
Thesis: "Identification and Characterization of Foxe3, a Forkhead Gene Critical in Vertebrate Lens Development".

August 1987-May 1992


Bachelor of Science in Electrical Engineering. Summa Cum Laude. Bachelor of Science in Mathematics. Summa Cum Laude. University of Maryland at College Park, Maryland.

Publications:


Rao, S., Tschen, J.A., Pearson, G.W., Markus, R., Brownell, I., (In press). Comparison of Treatment Options for a Monsel's Tattoo. Archives of Dermatology.

Brownell I and Strober B. Folate with methotrexate - big benefit, questionable cost. (In press) British Journal of Dermatology.

Irizarry E, Brownell I, Pomeranz MK. (In press) The "louse blouse" as a cause of erythroderma. Archives of Dermatology.

Abbasi NR, Brownell I, Fangman W. (2007 Jan). Familial multiple angiolipomatosis. Dermatol Online J, 13:(1): 3.

Brownell I, Fangman W. (2007 Jan). Hepatitis C Virus infection, type III cryoglobulinemia, and necrotizing vasculitis. Dermatol Online J, 13: (1):6.

Brownell I, Soter NA, Franks AG. (2007 Jan Familial linear scleroderma (en coup de sabre) responsive to antimalarials and narrowband ultraviolet B therapy.). Dermatol Online J, 13: (1) 11.
Brownell I, Pomeranz M, Ma L. Eumycetoma. (2005 Dec) Dermatol Online J., 30: 11(4) 10.

Medina-Martinez O, Brownell I, Amaya-Manzanares F, Hu Q, Behringer RR, Jamrich M. (2005 Oct) . Severe defects in proliferation and differentiation of lens cells in Foxe3 null mice. Mol Cell Biol, 25(20): 8854-63.

Zilinski C, Brownell I, Hashimoto R, Medina-Martinez O, Swindell EC, Jamrich M. (2004) Expression of FoxE4 and Rx visualizes the timing and dynamics of critical processes taking place during initial stages of vertebrate eye develop-ment. Dev Neurosci, 26(5-6): 294-307.

Tseng, H.T., Brownell, I., Hashimoto, R., El-Hodiri, H., Medina-Martinez, O., Shah, R., Zilinski, C., and Jamrich, M. (2004). Role of Fox genes during Xenopus embryogenesis. "The Vertebrate Organizer". H. Grunz (Ed.), Springer Verlag, 41-54.

Brownell I, Quan LT, Hsu S. (2003 Aug). Topical pimecrolimus in the treatment of seborrheic dermatitis. Dermatol Online J. 9(3): 13.

Yang D, Brownell I, Duvic M. (2003). Celecoxib-Induced Bullous Pemphigoid: Report Of The First Case. Internet J Dermatol, 2(1).

Pielop JA, Brownell I, Duvic M. (2003 Feb). Mycosis fungoides associated with malignant melanoma and dysplastic nevus syndrome. (2003 Feb). Int J Dermatol, 42(2): 116-22.

Semina EV*, Brownell I*, Mintz-Hittner HA, Murray J, Jamrich M. (2001). Muta-tions in the human forkhead transcription factor FOXE3 associated with anterior segment ocular dysgenesis and cataracts. Hum Mol Genet, 10: 231-236. *co-first authors

Brownell I, Dirksen M, Jamrich M. Forkhead (2000 Jun). Foxe3 maps to the dysgenetic lens locus and is critical in lens development and differentiation. Genesis, 27(2): 81-93.


Research Interests:


I am studying the molecular regulation of cell specification and patterning in skin development, and the regulation and maintenance of adult stem cells in the skin. I am using a genetic fate mapping and conditional mutagenesis.

PrintEmail This Page